The complement system in inflammatory bowel disease
U Jain, AR Otley, J Van Limbergen… - Inflammatory bowel …, 2014 - academic.oup.com
Complement is well appreciated to be a potent innate immune defense against microbes
and is important in the housekeeping act of removal of apoptotic and effete cells. It is also …
and is important in the housekeeping act of removal of apoptotic and effete cells. It is also …
Complement lectin pathway activation is associated with COVID-19 disease severity, independent of MBL2 genotype subgroups
L Hurler, Á Szilágyi, F Mescia, L Bergamaschi… - Frontiers in …, 2023 - frontiersin.org
Introduction While complement is a contributor to disease severity in severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) infections, all three complement …
respiratory syndrome coronavirus 2 (SARS-CoV-2) infections, all three complement …
From Gut to Brain: Uncovering Potential Serum Biomarkers Connecting Inflammatory Bowel Diseases to Neurodegenerative Diseases
OF Sarb, AD Sarb, M Iacobescu, IM Vlad… - International Journal of …, 2024 - mdpi.com
Inflammatory bowel diseases (IBDs) are characterized by chronic gastrointestinal
inflammation due to abnormal immune responses to gut microflora. The gut–brain axis is …
inflammation due to abnormal immune responses to gut microflora. The gut–brain axis is …
ADOA3R as a therapeutic target in experimental colitis: proof by validated high-density oligonucleotide microarray analysis
J Guzman, JG Yu, Z Suntres, A Bozarov… - Inflammatory bowel …, 2006 - academic.oup.com
Abstract Adenosine A3 receptors (ADOA3Rs) are emerging as novel purinergic targets for
treatment of inflammatory diseases. Our goal was to assess the protective effect of the …
treatment of inflammatory diseases. Our goal was to assess the protective effect of the …
Potential of myricetin to restore the immune balance in dextran sulfate sodium-induced acute murine ulcerative colitis
X Qu, Q Li, Y Song, A Xue, Y Liu, D Qi… - Journal of Pharmacy …, 2020 - academic.oup.com
Objectives Myricetin is a bioactive compound in many edible plants with anti-inflammatory
and anticarcinogenic activity. The current study aimed to determine the protective effects and …
and anticarcinogenic activity. The current study aimed to determine the protective effects and …
Plasma profiles in active systemic juvenile idiopathic arthritis: biomarkers and biological implications
XB Ling, JL Park, T Carroll, KD Nguyen, K Lau… - …, 2010 - Wiley Online Library
Systemic juvenile idiopathic arthritis (SJIA) is a chronic arthritis of children characterized by
a combination of arthritis and systemic inflammation. There is usually non‐specific …
a combination of arthritis and systemic inflammation. There is usually non‐specific …
Correlated expression of high-sensitivity C-reactive protein in relation to disease activity in inflammatory bowel disease: lack of differences between Crohn's disease …
L Zilberman, N Maharshak, Y Arbel, O Rogowski… - Digestion, 2006 - karger.com
Background/Aims: As opposed to regular C-reactive protein (CRP) assays, the introduction
of high-sensitivity ones has enabled us to detect low grade inflammation in patients with …
of high-sensitivity ones has enabled us to detect low grade inflammation in patients with …
[HTML][HTML] Serum protein profiling of early and advanced stage Crohn's disease
Crohn's disease (CD) represents a highly debilitating disease of difficult diagnosis and
increasing incidence. Serum protein profiling of early stage Crohn's disease (ES) CD was …
increasing incidence. Serum protein profiling of early stage Crohn's disease (ES) CD was …
Systemic Dosing of Virus-derived Serpin Improves Survival and Immunothrombotic Damage in Murine Colitis
L Zhang, JR Turk, H Monder, CR Woodrow… - bioRxiv, 2024 - biorxiv.org
Inflammatory bowel disease (IBD) is potentially life-threatening, with risk of bleeding,
clotting, infection, sepsis, cancer and toxic megacolon. Systemic and local immune and …
clotting, infection, sepsis, cancer and toxic megacolon. Systemic and local immune and …
[HTML][HTML] Comparison of two chemically-induced colitis-models in adult zebrafish, using optical projection tomography and novel transcriptional markers
S Haarder, PW Kania, TL Holm, M Ohtani… - Open Journal of …, 2016 - scirp.org
Crohn's disease and ulcerative colitis—inflammatory bowel diseases (IBD)—are chronic
conditions with an inadequately understood pathogenesis. Employing a set of novel …
conditions with an inadequately understood pathogenesis. Employing a set of novel …