The discovery of the carcinoembryonic antigen (CEA) as a tumor marker for colorectal
cancer some 50 years ago became the first step in the identification of a much larger family …

Context The introduction of novel imaging modalities has increased the detection of
oligometastatic prostate cancer (PCa) recurrence, potentially justifying the use of a …

The TRIPOD (Transparent Reporting of a multivariable prediction model for Individual
Prognosis Or Diagnosis) Statement includes a 22-item checklist, which aims to improve the …

Background In patients with resectable colorectal liver metastases (CRLM), the role of pre-
and postoperative systemic therapy continues to be debated. Previous studies have shown …

An extensive amount of information is currently available to clinical specialists, ranging from
details of clinical symptoms to various types of biochemical data and outputs of imaging …

Objectives To evaluate how often newly developed risk prediction models undergo external
validation and how well they perform in such validations. Study Design and Setting We …

Colorectal carcinoma (CRC) is the third most common cancer, and approximately 35%-55%
of patients with CRC will develop hepatic metastases during the course of their disease …

Background Initially, unresectable colorectal liver metastases can be resected after
response to chemotherapy. While cetuximab has been shown to increase response and …

Background Approximately 25% of patients with colorectal cancer (CRC) will have liver
metastases classified as synchronous or metachronous. There is no consensus on the …

Introduction Gait deficits are debilitating in people with Parkinson's disease (PwPD), which
inevitably deteriorate over time. Gait analysis is a valuable method to assess disease …