Articular cartilage serves as a low-friction, load-bearing tissue without the support with blood
vessels, lymphatics and nerves, making its repair a big challenge. Transforming growth …

Carrageenan is a class of naturally occurring sulphated polysaccharides, which is currently
a promising candidate in tissue engineering and regenerative medicine as it resemblances …

Once damaged, articular cartilage has a limited potential to repair. Clinically, a repair tissue
is formed, yet, it is often mechanically inferior fibrocartilage. The use of monolayer expanded …

The increase in global lifespan has in turn increased the prevalence of osteoarthritis which
is now the most common type of arthritis. Cartilage tissue located on articular joints erodes …

Articular cartilage (AC) covers the diarthrodial joints and is responsible for the mechanical
distribution of loads across the joints. The majority of its structure and function is controlled …

Musculoskeletal disorders represent a major cause of disability and morbidity globally and
result in enormous costs for health and social care systems. Development of cell-based …

One of the most important issues facing cartilage tissue engineering is the inability to move
technologies into the clinic. Despite the multitude of current research in the field, it is known …

Much of the mammalian skeleton is composed of bones that originate from cartilage
templates through endochondral ossification. Elucidating the mechanisms that control …

Articular cartilage is a physiologically non-self-renewing avascular tissue with a singular cell
type, the chondrocyte, which functions as the load-bearing surface of the arthrodial joint …

Cartilage damage is a key feature of degenerative joint disorders—primarily osteoarthritis
(OA)—and chronic inflammatory joint diseases, such as rheumatoid arthritis (RA) …