Recently, a new class of prokaryotic compartments, collectively called encapsulins or protein
nanocompartments, has been discovered. The shell proteins of these structures self …

Compartmentalization is both a fundamental principle of cellular organization and an
emerging theme in prokaryotic biology. Work in the past few decades has shown that protein …

Pyrococcus furiosus is a hyperthermophilic archaeal microorganism found near deep-sea
thermal vents and its optimal growth temperature of 100° C. Recently, a 38.8-kDa protein …

Cultures of hyperthermophilic archaea (order Thermococcales) have been analyzed by
electron microscopy and epifluorescence staining for the presence of virus-like particles. We …

The encapsulin nanocompartment from Rhodococcus erythropolis N771 (Reencapsulin)
was expressed and purified in wild‐type and C‐terminally His‐tagged forms. Negative …

Traditional views of synthetic biology often treat the cell as an unstructured container in
which biological reactions proceed uniformly. In reality, the organization of biological …

In 1994 a new class of prokaryotic compartments was discovered, collectively called
“encapsulins” or “nanocompartments”. Encapsulin shell protomer proteins self-assemble to …

The model archaeon Pyrococcus furiosus grows optimally near 100° C on carbohydrates
and peptides. Its genome sequence (NCBI) was determined 12 years ago. A genetically …

Tailed double-stranded DNA bacteriophages and herpesviruses build capsids by co-
assembling a major capsid protein with an internal scaffolding protein that then exits from …

One of the outstanding questions in biology today is the origin of viruses. We have
discovered a protein in the hyperthermophile Sulfolobus solfataricus while following …