Management of Clostridioides difficile infection in adults and challenges in clinical practice: review and comparison of current IDSA/SHEA, ESCMID and ASID …

EJ Bishop, R Tiruvoipati - Journal of Antimicrobial …, 2023 - academic.oup.com
Clostridioides difficile infection (CDI) remains a significant clinical challenge both in the
management of severe and severe-complicated disease and the prevention of recurrence …

Treatment of Clostridioides (Clostridium) difficile infection

O Jarmo, A Veli-Jukka, M Eero - Annals of medicine, 2020 - Taylor & Francis
Clostridioides (formerly: Clostridium) difficile infection (CDI) is a major cause of diarrhoea for
inpatients as well as outpatients. Usually, CDI is healthcare-associated but the number of …

Plasmid-mediated metronidazole resistance in Clostridioides difficile

IM Boekhoud, BVH Hornung, E Sevilla… - Nature …, 2020 - nature.com
Metronidazole was until recently used as a first-line treatment for potentially life-threatening
Clostridioides difficile (CD) infection. Although cases of metronidazole resistance have been …

Cost-effectiveness of Treatment Regimens for Clostridioides difficile Infection: An Evaluation of the 2018 Infectious Diseases Society of America Guidelines

R Rajasingham, EA Enns, A Khoruts… - Clinical infectious …, 2020 - academic.oup.com
Abstract Background In 2018, the Infectious Diseases Society of America (IDSA) published
guidelines for diagnosis and treatment of Clostridioides (formerly Clostridium) difficile …

Use of Oral Vancomycin for Clostridioides difficile Infection and the Risk of Vancomycin-Resistant Enterococci

VW Stevens, K Khader, K Echevarria… - Clinical Infectious …, 2020 - academic.oup.com
Background Vancomycin is now a preferred treatment for all cases of Clostridioides difficile
infection (CDI), regardless of disease severity. Concerns remain that a large-scale shift to …

[HTML][HTML] Recommendations and guidelines for the treatment of Clostridioides difficile infection in Taiwan

KS Wu, LS Syue, A Cheng, TY Yen, HM Chen… - Journal of Microbiology …, 2020 - Elsevier
Clostridioides difficile infection (CDI) is a major enteric disease associated with antibiotic
use and a leading cause of hospital-acquired infections worldwide. This is the first guideline …

What Is the Role for Metronidazole in the Treatment of Clostridium difficile Infection? Results From a National Cohort Study of Veterans With Initial Mild Disease

HJ Appaneal, AR Caffrey… - Clinical Infectious …, 2019 - academic.oup.com
Background Metronidazole may still be an appropriate therapeutic option for mild
Clostridium difficile infection (CDI) in select patients, but data are limited to guide clinicians …

Predictive factors, outcomes, and molecular epidemiology of Clostridioides difficile diarrhea in Brazilian hospitals

ES Girão, B de Melo Tavares, SA Dos Santos… - European Journal of …, 2021 - Springer
Little is known about the role of lineage of strains of Clostridioides difficile (CD) on the
clinical presentation of CD infection (CDI) in Latin America, especially regarding the …

Outcomes associated with recent guideline recommendations removing metronidazole for treatment of non-severe Clostridioides difficile infection: a retrospective …

CA Gentry, DL Campbell, RJ Williams - International Journal of …, 2021 - Elsevier
Abstract Objectives The 2017 Society for Healthcare Epidemiology of America (SHEA) and
Infectious Diseases Society of America (IDSA) Clinical Practice Guidelines for Clostridioides …

Microbiome-preserving antibiotics for the treatment of Clostridioides difficile infection: a systematic review and meta-analysis

AM Kravets, R Hanneke, RL Nelson - Techniques in Coloproctology, 2024 - Springer
Background Newer antibiotics that specifically target Clostridioides difficile while preserving
the host microbiome have emerged to treat C. difficile infection (CDI): cadazolid, fidaxomicin …