Resistant hypertension (RH) is defined as above-goal elevated blood pressure (BP) in a
patient despite the concurrent use of 3 antihypertensive drug classes, commonly including a …

Several articles have dealt with the importance and mechanisms of the sympathetic nervous
system alterations in experimental animal models of hypertension. This review addresses …

Background Conflicting blood pressure-lowering effects of catheter-based renal artery
denervation have been reported in patients with resistant hypertension. We compared the …

Background Renal denervation (RDN) with radiofrequency ablation substantially reduces
blood pressure in patients with treatment-resistant hypertension. We assessed the long-term …

Background: Although renal sympathetic denervation therapy has shown promising results
in patients with resistant hypertension, the human anatomy of peri-arterial renal nerves is …

Methods and system are provided for thermally-induced renal neuromodulation. Thermally-
induced renal neuromodulation may be achieved via direct and/or via indirect application of …

Arterial hypertension is the most prevalent modifiable risk factor associated with
cardiovascular morbidity and mortality. Although antihypertensive drugs are widely …

Aug. 16, 2007, noW Pat. No. 7,717,948, Which is a(Continued) continuation of application
No. 11/504,117,? led on continuatlon-m-part of apphcation No. 10/408,665,? led on Apr. 8 …

Methods and apparatus are provided for intravascularly-induced neuromodulation or
denervation. Neuromodulation may be achieved via direct and/or via indirect application of …

Methods and apparatus are provided for renal neuromodulation using a pulsed electric field
to effectuate electroporation or electrofusion. It is expected that renal neuromodulation (eg …