After its discovery as a key controller of metabolic function, leptin has been later extensively
implicated in additional functions including important modulatory activities on the innate and …

There is strong evidence indicating that excess adiposity negatively impacts immune
function and host defence in obese individuals. This is a review of research findings …

Leptin, discovered through positional cloning 15 years ago, is an adipocyte-secreted
hormone with pleiotropic effects in the physiology and pathophysiology of energy …

Leptin is an adipocyte-derived hormone/cytokine that links nutritional status with
neuroendocrine and immune functions. In humans, leptin influences energy homeostasis …

Rationale: The developed world is currently facing an epidemic of obesity. With the
increased prevalence of obesity has come the recognition that obesity is a risk factor for …

Leptin regulates energy homeostasis and reproductive, neuroendocrine, immune, and
metabolic functions. In this review, we describe the role of leptin in human physiology and …

The past few years of research on leptin have provided important information on the link
between metabolism and immune homeostasis. Adipocytes influence not only the endocrine …

The world is now experiencing an epidemic of obesity. Although the effects of obesity on the
development of metabolic and cardiovascular problems are well studied, much less is …

The prevalence and incidence of asthma have increased among obese children and adults,
particularly among women. Obesity seems to be a predisposing factor for the development …

Leptin, a pleiotropic protein has long been recognized to play an important role in the
regulation of energy homeostasis, metabolism, neuroendocrine function, and other …