Axons are ultrathin membrane cables that are specialized for the conduction of action
potentials. Although their diameter is variable along their length, how their morphology is …

Computational modeling of signal propagation in neurons is critical to our understanding of
basic principles underlying brain organization and activity. Exploring these models is used …

Accurate estimation of action potential (AP)-related metabolic cost is essential for
understanding energetic constraints on brain connections and signaling processes. Most …

CNS injury may lead to permanent functional deficits because it is still not possible to
regenerate axons over long distances and accurately reconnect them with an appropriate …

This study aims to provide an overview of the recent developments in understanding
multiscale traumatic brain injury (TBI) mechanisms from a multidisciplinary perspective. TBI …

Abstract Background Focal Axonal Swellings arise in several leading neurodegenerative
diseases of the central nervous system and are hallmark features of concussions and …

Axonal swellings are almost universal in neurodegenerative diseases of the central nervous
system, including Alzheimer's and Parkinson's disease. Concussions and traumatic brain …

Retinal ganglion cell axons of the DBA/2J mouse model of glaucoma, a model characterized
by extensive neuroinflammation, preserve synaptic contacts with their subcortical targets for …

This article communicates results on regular depolarization cascades in periodically kicked
feedforward chains of excitable two-dimensional FitzHugh–Nagumo systems driven by …

Axons are thought to be ultrathin membrane cables of a relatively uniform diameter,
designed to conduct electrical signals, or action potentials. Here, we demonstrate that …