State-of-the-art of profiling immune contexture in the era of multiplexed staining and digital analysis to study paraffin tumor tissues
ER Parra, A Francisco-Cruz, II Wistuba - Cancers, 2019 - mdpi.com
Multiplexed platforms for multiple epitope detection have emerged in the last years as very
powerful tools to study tumor tissues. These revolutionary technologies provide important …
powerful tools to study tumor tissues. These revolutionary technologies provide important …
MALDI mass spectrometry imaging: A cutting‐edge tool for fundamental and clinical histopathology
R Longuespée, R Casadonte… - PROTEOMICS …, 2016 - Wiley Online Library
Histopathological diagnoses have been done in the last century based on hematoxylin and
eosin staining. These methods were complemented by histochemistry, electron microscopy …
eosin staining. These methods were complemented by histochemistry, electron microscopy …
Rapid MALDI mass spectrometry imaging for surgical pathology
Matrix assisted laser desorption ionization mass spectrometry imaging (MALDI MSI) is an
emerging analytical technique, which generates spatially resolved proteomic and …
emerging analytical technique, which generates spatially resolved proteomic and …
Charge distribution between different classes of glycerophospolipids in MALDI-MS imaging
MS Boskamp, J Soltwisch - Analytical chemistry, 2020 - ACS Publications
Matrix-assisted laser desorption ionization mass spectrometry imaging (MALDI-MSI) is
widely used to visualize and analyze the distribution of membrane lipids in an increasingly …
widely used to visualize and analyze the distribution of membrane lipids in an increasingly …
Recognition and avoidance OF ION source‐generated artifacts IN lipidomics analysis
C Hu, W Luo, J Xu, X Han - Mass spectrometry reviews, 2022 - Wiley Online Library
Lipid research is attracting more and more attention as various key roles and novel
biological functions of lipids have been demonstrated and discovered in the organism. Mass …
biological functions of lipids have been demonstrated and discovered in the organism. Mass …
Trends in mass spectrometry imaging for cardiovascular diseases
STP Mezger, AMA Mingels, O Bekers… - Analytical and …, 2019 - Springer
Mass spectrometry imaging (MSI) is a widely established technology; however, in the
cardiovascular research field, its use is still emerging. The technique has the advantage of …
cardiovascular research field, its use is still emerging. The technique has the advantage of …
Seeing is Believing: Developing Multimodal Metabolic Insights at the Molecular Level
This outlook explores how two different molecular imaging approaches might be combined
to gain insight into dynamic, subcellular metabolic processes. Specifically, we discuss how …
to gain insight into dynamic, subcellular metabolic processes. Specifically, we discuss how …
Enterohemorrhagic Escherichia coli and a Fresh View on Shiga Toxin-Binding Glycosphingolipids of Primary Human Kidney and Colon Epithelial Cells and Their …
J Detzner, G Pohlentz, J Müthing - International Journal of Molecular …, 2022 - mdpi.com
Enterohemorrhagic Escherichia coli (EHEC) are the human pathogenic subset of Shiga
toxin (Stx)-producing E. coli (STEC). EHEC are responsible for severe colon infections …
toxin (Stx)-producing E. coli (STEC). EHEC are responsible for severe colon infections …
Shiga toxin-glycosphingolipid interaction: Status quo of research with focus on primary human brain and kidney endothelial cells
N Legros, G Pohlentz, D Steil, J Müthing - International Journal of Medical …, 2018 - Elsevier
Shiga toxin (Stx)-mediated injury of the kidneys and the brain represent the major
extraintestinal complications in humans upon infection by enterohemorrhagic Escherichia …
extraintestinal complications in humans upon infection by enterohemorrhagic Escherichia …
Direct visualization of neurotransmitters in rat brain slices by desorption electrospray ionization mass spectrometry imaging (DESI-MS)
AMAP Fernandes, PH Vendramini… - Journal of The …, 2016 - ACS Publications
Mass spectrometry imaging (MSI) of neurotransmitters has so far been mainly performed by
matrix-assisted laser desorption/ionization (MALDI) where derivatization reagents …
matrix-assisted laser desorption/ionization (MALDI) where derivatization reagents …