[HTML][HTML] In-vitro and in-silico studies of annelated 1, 4, 7, 8-tetrahydroazocine ester derivatives as nanomolar selective inhibitors of human butyrylcholinesterase
Based on previous finding showing 2, 3, 6, 11-tetrahydro-1H-azocino [4, 5-b] indole as
suitable scaffold of novel inhibitors of acetylcholinesterase (AChE), a main target of drugs for …
suitable scaffold of novel inhibitors of acetylcholinesterase (AChE), a main target of drugs for …
Synthesis of heteroannulated azocine derivatives
Publisher Summary This chapter reviews that azocinoindoles have been investigated
extensively due to the host of alkaloids with an azocinoindole fragment in their structure. The …
extensively due to the host of alkaloids with an azocinoindole fragment in their structure. The …
Novel chemistry of β-carbolines. Expedient synthesis of polycyclic scaffolds
A Gonzalez-Gomez, G Domínguez, J Perez-Castells - Tetrahedron, 2009 - Elsevier
Functionalization of β-carbolines is a challenge as numerous natural alkaloids with different
biological activities present this heterocycle. The RCM is used herein with allyl-, vinyl …
biological activities present this heterocycle. The RCM is used herein with allyl-, vinyl …
Ester derivatives of annulated tetrahydroazocines: A new class of selective acetylcholinesterase inhibitors
A series of ester derivatives of annulated tetrahydroazocines, namely 2, 3, 6, 11-tetrahydro-
1H-azocino [4, 5-b] indoles (5–10), 2, 3, 6, 7-tetrahydro-1H-azocino [5, 4-b] indoles (11–14) …
1H-azocino [4, 5-b] indoles (5–10), 2, 3, 6, 7-tetrahydro-1H-azocino [5, 4-b] indoles (11–14) …
A novel synthesis of hexahydroazoninoindoles using activated alkynes in an azepine ring expansion
LG Voskressensky, SV Akbulatov, TN Borisova… - Tetrahedron, 2006 - Elsevier
A novel synthesis of hexahydroazoninoindoles using activated alkynes in an azepine ring
expansion - ScienceDirect Skip to main contentSkip to article Elsevier logo Journals & Books …
expansion - ScienceDirect Skip to main contentSkip to article Elsevier logo Journals & Books …
Transformations of tetrahydro-pyrido[4,3-d]pyrimidines [b]-condensed with isoxazole, thiazole, thiadiazole, and triazole units under the action of activated alkynes
LG Voskressensky, TN Borisova, MV Ovcharov… - Chemistry of …, 2008 - Springer
It has been established that 5-vinyl-substituted (NR, N-vinylaminomethyl) isoxazolo
(thiazolo, thiadiazolo) pyrimidines are formed when tetrahydropyrido [3, 4-d] pyrimidines …
(thiazolo, thiadiazolo) pyrimidines are formed when tetrahydropyrido [3, 4-d] pyrimidines …
Novel domino reactions in β-carbolines with triple bonded dienophiles
Á González-Gómez, G Domínguez, U Amador… - Tetrahedron …, 2008 - Elsevier
Vinylpyrrolo-[2, 1-a]-β-carbolines 1 give different products upon reaction with dienophiles.
With dimethyl acetylenedicarboxylate (DMAD), a novel domino process takes place …
With dimethyl acetylenedicarboxylate (DMAD), a novel domino process takes place …
Recyclization of benzofuropyridines by the action of activated alkynes in the synthesis of spiro [benzofuropyridines], representatives of a new class of …
LG Voskressensky, SA Kovaleva, TN Borisova… - Chemistry of …, 2013 - Springer
A study was carried out on the domino transformations of tetrahydrobenzofuro [2, 3-c]
pyridines and tetrahydrobenzofuro [3, 2-c] pyridines by the action of activated alkynes in …
pyridines and tetrahydrobenzofuro [3, 2-c] pyridines by the action of activated alkynes in …
Synthesis and Reactivity of a Novel Class of Long-Lived Ammonium Ylides: Derivatives of Benzo[b]pyrrolo[2,1-f][1.6]naphthyridine
LG Voskressensky, IV Vorobiev… - The Journal of …, 2008 - ACS Publications
Reaction of 10-cyanotetrahydrobenzo [b][1, 6] naphthyridines (1− 6) with activated alkynes
affords stable benzo [b] pyrrolo [2, 1-f][1, 6] naphthyridine-4-ium ylides (7− 14) in moderate …
affords stable benzo [b] pyrrolo [2, 1-f][1, 6] naphthyridine-4-ium ylides (7− 14) in moderate …
Synthesis of 4-amino-substituted tetrahydropyrimido[4,5-d]azocines
LG Voskressensky, MV Ovcharov, TN Borisova… - Chemistry of …, 2013 - Springer
A method for the preparation of 4-amino-substituted tetrahydropyrimido [4, 5-d] azocines
containing an aromatic pyrimidine fragment has been developed. It was established that …
containing an aromatic pyrimidine fragment has been developed. It was established that …