The intestinal microbiota: antibiotics, colonization resistance, and enteric pathogens

S Kim, A Covington, EG Pamer - Immunological reviews, 2017 - Wiley Online Library
The human gastrointestinal tract hosts a diverse network of microorganisms, collectively
known as the microbiota that plays an important role in health and disease. For instance, the …

Aim, load, fire: the type VI secretion system, a bacterial nanoweapon

FR Cianfanelli, L Monlezun, SJ Coulthurst - Trends in microbiology, 2016 - cell.com
Bacteria utilise specialised protein secretion systems to interact with host organisms,
competitor bacteria, and the environment. The Type VI secretion system (T6SS) is a versatile …

[HTML][HTML] A comprehensive review of non-enterica subspecies of Salmonella enterica

A Lamas, JM Miranda, P Regal, B Vázquez… - Microbiological …, 2018 - Elsevier
Salmonella is a major foodborne pathogen with a complex nomenclature. This genus is
composed of two species, S. enterica and S. bongori. S. enterica is divided into six …

Type VI secretion system effectors: poisons with a purpose

AB Russell, SB Peterson, JD Mougous - Nature reviews microbiology, 2014 - nature.com
The type VI secretion system (T6SS) mediates interactions between a broad range of Gram-
negative bacterial species. Recent studies have led to a substantial increase in the number …

A view to a kill: the bacterial type VI secretion system

BT Ho, TG Dong, JJ Mekalanos - Cell host & microbe, 2014 - cell.com
The bacterial type VI secretion system (T6SS) is an organelle that is structurally and
mechanistically analogous to an intracellular membrane-attached contractile phage tail …

Salmonella Typhimurium utilizes a T6SS-mediated antibacterial weapon to establish in the host gut

TG Sana, N Flaugnatti, KA Lugo… - Proceedings of the …, 2016 - National Acad Sciences
The mammalian gastrointestinal tract is colonized by a high-density polymicrobial
community where bacteria compete for niches and resources. One key competition strategy …

A type VI secretion system of Pseudomonas aeruginosa targets a toxin to bacteria

RD Hood, P Singh, FS Hsu, T Güvener, MA Carl… - Cell host & …, 2010 - cell.com
The functional spectrum of a secretion system is defined by its substrates. Here we analyzed
the secretomes of Pseudomonas aeruginosa mutants altered in regulation of the Hcp …

Type VI secretion and anti-host effectors

A Hachani, TE Wood, A Filloux - Current opinion in microbiology, 2016 - Elsevier
Highlights•T6SS is a secretion system involved in the virulence of bacterial pathogens.•This
versatile weapon can target both prokaryotic and eukaryotic cells.•The T6SS tail/spike …

Embracing Diversity: Differences in Virulence Mechanisms, Disease Severity, and Host Adaptations Contribute to the Success of Nontyphoidal Salmonella as a …

RA Cheng, CR Eade, M Wiedmann - Frontiers in microbiology, 2019 - frontiersin.org
Not all Salmonella enterica serovars cause the same disease. S. enterica represents an
incredibly diverse species comprising> 2,600 unique serovars. While some S. enterica …

RNA-seq Brings New Insights to the Intra-Macrophage Transcriptome of Salmonella Typhimurium

S Srikumar, C Kröger, M Hébrard, A Colgan… - PLoS …, 2015 - journals.plos.org
Salmonella enterica serovar Typhimurium is arguably the world's best-understood bacterial
pathogen. However, crucial details about the genetic programs used by the bacterium to …