Sex differences in depression: Insights from clinical and preclinical studies
Depression represents a global mental health concern, and disproportionally affects women
as they are twice more likely to be diagnosed than men. In this review, we provide a …
as they are twice more likely to be diagnosed than men. In this review, we provide a …
Postpartum depression
DE Stewart, S Vigod - New England Journal of Medicine, 2016 - Mass Medical Soc
Key Clinical Points Postpartum Depression Postpartum depression is a common, disabling,
and treatable problem that affects the woman, infant, and family. Sensitive inquiry about …
and treatable problem that affects the woman, infant, and family. Sensitive inquiry about …
Brexanolone injection in post-partum depression: two multicentre, double-blind, randomised, placebo-controlled, phase 3 trials
S Meltzer-Brody, H Colquhoun, R Riesenberg… - The Lancet, 2018 - thelancet.com
Background Post-partum depression is associated with substantial morbidity, and improved
pharmacological treatment options are urgently needed. We assessed brexanolone …
pharmacological treatment options are urgently needed. We assessed brexanolone …
Postpartum psychiatric disorders
S Meltzer-Brody, LM Howard, V Bergink… - Nature Reviews …, 2018 - nature.com
Pregnancy is a complex and vulnerable period that presents a number of challenges to
women, including the development of postpartum psychiatric disorders (PPDs). These …
women, including the development of postpartum psychiatric disorders (PPDs). These …
Brexanolone (SAGE-547 injection) in post-partum depression: a randomised controlled trial
S Kanes, H Colquhoun, H Gunduz-Bruce, S Raines… - The Lancet, 2017 - thelancet.com
Background Post-partum depression is a serious mood disorder in women that might be
triggered by peripartum fluctuations in reproductive hormones. This phase 2 study …
triggered by peripartum fluctuations in reproductive hormones. This phase 2 study …
The neurobiology of postpartum anxiety and depression
JL Pawluski, JS Lonstein, AS Fleming - Trends in neurosciences, 2017 - cell.com
Ten to twenty percent of postpartum women experience anxiety or depressive disorders,
which can have detrimental effects on the mother, child, and family. Little is known about the …
which can have detrimental effects on the mother, child, and family. Little is known about the …
Giving birth during the COVID‐19 pandemic: The impact on birth satisfaction and postpartum depression
C Mariño‐Narvaez… - … of Gynecology & …, 2021 - Wiley Online Library
Objective To understand how giving birth during the coronavirus disease 2019 (COVID‐19)
pandemic affected women based on birth parameters (gestational age, type of birth and …
pandemic affected women based on birth parameters (gestational age, type of birth and …
Clinical phenotypes of perinatal depression and time of symptom onset: analysis of data from an international consortium
KT Putnam, M Wilcox, E Robertson-Blackmore… - The Lancet …, 2017 - thelancet.com
Background The perinatal period is a time of high risk for onset of depressive disorders and
is associated with substantial morbidity and mortality, including maternal suicide. Perinatal …
is associated with substantial morbidity and mortality, including maternal suicide. Perinatal …
Risk factors of postpartum depression and depressive symptoms: umbrella review of current evidence from systematic reviews and meta-analyses of observational …
BackgroundEvidence on risk factors for postpartum depression (PPD) are fragmented and
inconsistent. AimsTo assess the strength and credibility of evidence on risk factors of PPD …
inconsistent. AimsTo assess the strength and credibility of evidence on risk factors of PPD …
[HTML][HTML] Effect of brexanolone on depressive symptoms, anxiety, and insomnia in women with postpartum depression: Pooled analyses from 3 double-blind …
CN Epperson, DR Rubinow, S Meltzer-Brody… - Journal of Affective …, 2023 - Elsevier
Background Brexanolone is currently the only treatment specifically approved for postpartum
depression (PPD) in the United States, based on the results from one Phase 2 and two …
depression (PPD) in the United States, based on the results from one Phase 2 and two …