Diet and inflammation in cognitive ageing and Alzheimer's disease

AM McGrattan, B McGuinness, MC McKinley… - Current nutrition …, 2019 - Springer
Abstract Purpose of Review Nutrition is known to modulate the immune system and may
alter neuroinflammatory processes implicated in the pathogenesis of Alzheimer's disease …

Chinese herbal medicine for coronavirus disease 2019: A systematic review and meta-analysis

X Xiong, P Wang, K Su, WC Cho, Y Xing - Pharmacological research, 2020 - Elsevier
Abstract Currently, coronavirus disease 2019 (COVID-19), which can lead to severe
respiratory failure and death, is now a global pandemic with no specific anti-viral drugs or …

Anti-inflammatory and Anti-oxidant Activity of Hidrox® in Rotenone-Induced Parkinson's Disease in Mice

R Siracusa, M Scuto, R Fusco, A Trovato, ML Ontario… - Antioxidants, 2020 - mdpi.com
Background: In developed countries, the extension of human life is increasingly
accompanied by a progressive increase in neurodegenerative diseases, most of which do …

Loop between NLRP3 inflammasome and reactive oxygen species

A Dominic, NT Le, M Takahashi - Antioxidants & Redox Signaling, 2022 - liebertpub.com
Significance: Inflammasomes are cytosolic multiprotein complexes that mediate innate
immune pathways. Inflammasomes activate inflammatory caspases and regulate …

The gut microbiome–derived metabolite trimethylamine N-oxide modulates neuroinflammation and cognitive function with aging

VE Brunt, TJ LaRocca, AE Bazzoni, ZJ Sapinsley… - GeroScience, 2021 - Springer
Aging is associated with declines in cognitive performance, which are mediated in part by
neuroinflammation, characterized by astrocyte activation and higher levels of pro …

[HTML][HTML] CMS121, a fatty acid synthase inhibitor, protects against excess lipid peroxidation and inflammation and alleviates cognitive loss in a transgenic mouse model …

G Ates, J Goldberg, A Currais, P Maher - Redox Biology, 2020 - Elsevier
The oxidative degradation of lipids has been shown to be implicated in the progression of
several neurodegenerative diseases and modulating lipid peroxidation may be efficacious …

Healthy brain, healthy life: a review of diet and exercise interventions to promote brain health and reduce Alzheimer's disease risk

BJ Baranowski, DM Marko, RK Fenech… - Applied Physiology …, 2020 - cdnsciencepub.com
With the world's population aging at a rapid rate, the prevalence of Alzheimer's disease (AD)
has significantly increased. These statistics are alarming given recent evidence that a third …

[HTML][HTML] Nutrition and the ageing brain: Moving towards clinical applications

E Flanagan, D Lamport, L Brennan, P Burnet… - Ageing Research …, 2020 - Elsevier
The global increases in life expectancy and population have resulted in a growing ageing
population and with it a growing number of people living with age-related …

Health benefits, food applications, and sustainability of microalgae-derived N-3 PUFA

Y Liu, X Ren, C Fan, W Wu, W Zhang, Y Wang - Foods, 2022 - mdpi.com
Today's consumers are increasingly aware of the beneficial effects of n-3 PUFA in
preventing, delaying, and intervening various diseases, such as coronary artery disease …

Mid-life microbiota crises: middle age is associated with pervasive neuroimmune alterations that are reversed by targeting the gut microbiome

M Boehme, M van de Wouw, TFS Bastiaanssen… - Molecular …, 2020 - nature.com
Male middle age is a transitional period where many physiological and psychological
changes occur leading to cognitive and behavioural alterations, and a deterioration of brain …