[HTML][HTML] A review on selenium nanoparticles and their biomedical applications
Nanotechnology has enormous promise for a wide range of applications in biology.
Nanoparticles (NPs) have the benefit of improving bioactivity, decreasing toxicity, allowing …
Nanoparticles (NPs) have the benefit of improving bioactivity, decreasing toxicity, allowing …
Selenium-analogs based on natural sources as cancer-associated carbonic anhydrase isoforms IX and XII inhibitors
N Astrain-Redin, N Paoletti, D Plano… - Journal of enzyme …, 2023 - Taylor & Francis
In the relentless search for new cancer treatments, organoselenium compounds, and
carbonic anhydrase (CA) inhibitors have emerged as promising drug candidates. CA …
carbonic anhydrase (CA) inhibitors have emerged as promising drug candidates. CA …
Therapeutic cysteine protease inhibitors: a patent review (2018–present)
G Barchielli, A Capperucci, D Tanini - Expert Opinion on …, 2024 - Taylor & Francis
Introduction Cysteine proteases are involved in a broad range of biological functions,
ranging from extracellular matrix turnover to immunity. Playing an important role in the onset …
ranging from extracellular matrix turnover to immunity. Playing an important role in the onset …
Organic selenocompounds: are they the panacea for human illnesses?
The selenium element is essential to some life forms and its biological-chemistry function is
mainly performed by the selenol/selenolate moiety (–SeH/–Se–) in a few selenoproteins …
mainly performed by the selenol/selenolate moiety (–SeH/–Se–) in a few selenoproteins …
Tail approach synthesis of triazolylthiazolotriazole bearing benzenesulfonamides as carbonic anhydrase inhibitors capable of inducing apoptosis
Inhibition of human carbonic anhydrase (hCA) isoform IX with concurrent induction of
apoptosis is a promising approach for targeting cancer in humans. Prompted by the scope …
apoptosis is a promising approach for targeting cancer in humans. Prompted by the scope …
Inhibition studies with simple and complex (in)organic anions of the γ-carbonic anhydrase from Mammaliicoccus (Staphylococcus) sciuri, MscCAγ
The γ-carbonic anhydrase (CA, EC 4.2. 1.1) from the pathogenic bacterium,
Mammaliicoccus (Staphylococcus) sciuri (MscCAγ) was recently cloned and purified by our …
Mammaliicoccus (Staphylococcus) sciuri (MscCAγ) was recently cloned and purified by our …
[HTML][HTML] Leveraging SARS-CoV-2 Main Protease (Mpro) for COVID-19 Mitigation with Selenium-Based Inhibitors
The implementation of innovative approaches is crucial in an ongoing endeavor to mitigate
the impact of COVID-19 pandemic. The present study examines the strategic application of …
the impact of COVID-19 pandemic. The present study examines the strategic application of …
An alternative approach to selenides and diselenides from Se (0) and epoxides/aziridines under sustainable conditions
A Capperucci, A Petrucci, D Tanini - Arkivoc, 2023 - flore.unifi.it
The on-water reduction of elemental selenium promoted by rongalite (sodium
hydroxymethanesulfinate)/sodium hydroxide provided selenide anions, which led to a …
hydroxymethanesulfinate)/sodium hydroxide provided selenide anions, which led to a …
Thia‐and Seleno‐Michael reactions for the synthesis of Carbonic anhydrases inhibitors
A Angeli, A Occhini, G Renzi, A Capperucci… - ChemMedChem - Wiley Online Library
Novel chalcogen‐containing amides and esters bearing the benzenesulfonamide moiety
have been synthesised upon nucleophilic conjugate addition of thiols and selenols to …
have been synthesised upon nucleophilic conjugate addition of thiols and selenols to …
[PDF][PDF] Biomedical Technology
Nanotechnology has enormous promise for a wide range of applications in biology.
Nanoparticles (NPs) have the benefit of improving bioactivity, decreasing toxicity, allowing …
Nanoparticles (NPs) have the benefit of improving bioactivity, decreasing toxicity, allowing …