Quantitative phase imaging (QPI) is a label-free, wide-field microscopy approach with
significant opportunities for biomedical applications. QPI uses the natural phase shift of light …

Label-free imaging uses inherent contrast mechanisms within cells to create image contrast
without introducing dyes/labels, which may confound results. Quantitative phase imaging is …

Label-free cell analysis is essential to personalized genomics, cancer diagnostics, and drug
development as it avoids adverse effects of staining reagents on cellular viability and cell …

Recent studies reveal that lateral mitochondrial transfer, the movement of mitochondria from
one cell to another, can affect cellular and tissue homeostasis. Most of what we know about …

High throughput drug screening is an established approach to investigate tumor biology and
identify therapeutic leads. Traditional platforms use two-dimensional cultures which do not …

Scar tissue size following myocardial infarction is an independent predictor of
cardiovascular outcomes, yet little is known about factors regulating scar size. We …

The viscoelastic properties of mammalian cells can vary with biological state, such as during
the epithelial-to-mesenchymal (EMT) transition in cancer, and therefore may serve as a …

In the last decades, a wide multitude of research activity has been focused on the
development of new drugs, and devoted to overcome the challenges of high cost and low …

Ampk is an energy gatekeeper that responds to decreases in ATP by inhibiting energy-
consuming anabolic processes and promoting energy-generating catabolic processes …

Quantitative phase microscopy (QPM) enables studies of living biological systems without
exogenous labels. To increase the utility of QPM, machine-learning methods have been …