'2005 CMA Media Inc. Can J Surg, Vol. 48, No. 4, August 2005 319 terial intima that
develops in both the epicardial and intramyocardial arteries of the transplanted heart. The …

Cardiac transplantation has become limited by a critical shortage of suitable organs from
brain-dead donors. Reports describing the successful clinical transplantation of hearts …

BACKGROUND: Cardiac allograft vasculopathy (CAV) is primarily immune-mediated. We
investigated the role of cellular rejection in CAV development. METHODS: The study …

Endothelial injury plays a central role in the pathophysiologic mechanisms underlying
cardiac allograft vasculopathy (CAV). Although the accelerated course of CAV and its …

Background Adverse fibrotic remodeling is detrimental to myocardial health and a reliable
method for monitoring the development of fibrotic remodeling may be desirable during the …

Ischemia–reperfusion injury is an inevitable event during organ transplantation and
represents a primary risk factor for the development of early graft dysfunction in lung, heart …

BACKGROUND: Acute rejection increases the inflammatory burden of the transplanted
organ and predisposes to cardiac allograft vasculopathy (CAV). In this study we aim to …

The prevalence of heart failure is increasing, and the prognosis of end-stage heart failure
remains dismal. The gold-standard therapy in end-stage heart failure remains cardiac …

Background: Myocardial fibrosis is a well-described histopathologic feature in heart
transplant recipients. Whether myocardial fibrosis in heart transplant recipients is …

This review presents an integrated approach to the analysis of myocardial ischemia and
reperfusion injury and the modulating influence of myocardial conditioning during the …