Environmental risk factors have been implicated in adverse health effects. Previous
epidemiological studies on environmental risk factors mainly analyzed the impact of single …

Humans are exposed to a diverse mixture of chemical and non-chemical exposures across
their lifetimes. Well-designed epidemiology studies as well as sophisticated exposure …

Background The evaluation of the chemical impact on human health is usually constrained
to the analysis of the health effects of exposure to a single chemical or a group of similar …

Experimental evidence has shown that per-and polyfluoroalkyl substances (PFAS)
alternatives and mixtures may exert hepatotoxic effects in animals. However …

Background It is well-documented that heavy metals are associated with cardiovascular
disease (CVD). However, there is few studies exploring effect of metal mixture on CVD …

Background Hypertensive disorders of pregnancy (HDP), defined here as hypertensive
disorders with onset in pregnancy (ie, gestational hypertension, preeclampsia, and …

Current studies on environmental chemistry mainly focus on a single stressor or single
group of stressors, which does not reflect the multiple stressors in the dynamic exposome we …

Background Maternal and neonatal thyroid function is critical for growth and
neurodevelopment. Exposure to individual per-and polyfluoroalkyl substances (PFAS) can …

Background A growing number of epidemiologic studies have estimated associations
between type 2 diabetes mellitus and exposure to metals. However, studies on the …

Abstract Knowledge of the role in cancer etiology of environmental exposures as pesticides
is a prerequisite for primary prevention. We review 63 epidemiological studies on exposure …