Advances in copper complexes as anticancer agents

C Santini, M Pellei, V Gandin, M Porchia… - Chemical …, 2014 - ACS Publications
Medicinal inorganic chemistry offers additional opportunities for the design of therapeutic
agents not accessible to organic compounds. 1− 3 The wide range of coordination numbers …

First-row transition metal compounds containing benzimidazole ligands: An overview of their anticancer and antitumor activity

D Hernández-Romero, S Rosete-Luna… - Coordination Chemistry …, 2021 - Elsevier
Cancer can be defined as an irregular functioning of the cell cycle that results in a
progressive loss of cell differentiation and uncontrolled cell growth. Moreover, despite …

A novel palladium (II) antitumor agent: Synthesis, characterization, DFT perspective, CT-DNA and BSA interaction studies via in-vitro and in-silico approaches

M Feizi-Dehnayebi, E Dehghanian… - … Acta Part A: Molecular …, 2021 - Elsevier
Since numerous people annually pass away due to cancer, research in this field is essential.
Thus a newly made and water like palladium (II) complex of formula [Pd (phen)(acac)] NO 3 …

New ruthenium (II) arene complexes of anthracenyl-appended diazacycloalkanes: effect of ligand intercalation and hydrophobicity on DNA and protein binding and …

M Ganeshpandian, R Loganathan, E Suresh… - Dalton …, 2014 - pubs.rsc.org
A series of half-sandwich Ru (II) arene complexes of the type [Ru (η6-arene)(L) Cl](PF6) 1–
4, where arene is benzene (1, 2) or p-cymene (3, 4) and L is N-methylhomopiperazine (L1) …

Interactions of copper complexes with nucleic acids

A Erxleben - Coordination Chemistry Reviews, 2018 - Elsevier
Covalent or non-covalent interactions with DNA are the basis for many potential biomedical
applications of copper complexes, ranging from DNA structural probes and footprinting …

Mitochondria-targeted BODIPY dyes for small molecule recognition, bio-imaging and photodynamic therapy

S Wang, L Gai, Y Chen, X Ji, H Lu, Z Guo - Chemical Society Reviews, 2024 - pubs.rsc.org
Mitochondria are essential for a diverse array of biological functions. There is increasing
research focus on developing efficient tools for mitochondria-targeted detection and …

LVVO-Ethyl Maltol-Based Metallodrugs (L2– = Tridentate ONO Ligands): Hydrophobicity, Hydrolytic Stability, and Cytotoxicity via ROS-Mediated Apoptosis

G Sahu, SA Patra, PD Pattanayak… - Inorganic …, 2023 - ACS Publications
Four new oxidovanadium [VVOL1–4 (ema)] complexes (1–4) have been synthesized using
tridentate binegative ONO donor ligands H2L1–4 [H2L1:(E)-N′-(2-hydroxybenzylidene) …

Mixed ligand copper (II) complexes of 1, 10-phenanthroline with tridentate phenolate/pyridyl/(benz) imidazolyl Schiff base ligands: Covalent vs non-covalent DNA …

C Rajarajeswari, M Ganeshpandian… - Journal of inorganic …, 2014 - Elsevier
A series of copper (II) complexes of the types [Cu (L)(phen)](ClO 4) 1–2, where HL is a
tridentate ligand with two nitrogen and one oxygen donor atoms (2NO) such as 2-(2-(1H …

Evaluation of DNA/BSA interaction and in vitro cell cytotoxicity of μ2-oxido bridged divanadium (V) complexes containing ONO donor ligands

SA Patra, A Banerjee, G Sahu, M Mohanty… - Journal of Inorganic …, 2022 - Elsevier
Two new μ 2-oxido bridged divanadium (V) complexes,[VV 2 O 3 (L 1, 2) 2](1 and 2) have
been synthesized using bi-negative tridentate ONO-donor ligands, H 2 L 1, 2 (H 2 L 1= 4-tert …

Synthesis, crystal structure, DNA interaction and anticancer activity of tridentate copper (II) complexes

GY Li, KJ Du, JQ Wang, JW Liang, JF Kou… - Journal of Inorganic …, 2013 - Elsevier
Three new tridentate copper (II) complexes [Cu (dthp) Cl2](1)(dthp= 2, 6-di (thiazol-2-yl)
pyridine),[Cu (dmtp) Cl2](2)(dmtp= 2, 6-di (5-methyl-4H-1, 2, 4-triazol-3-yl) pyridine) and [Cu …