Size-Dependent In Vivo Transport of Nanoparticles: Implications for Delivery, Targeting, and Clearance

M Xu, Y Qi, G Liu, Y Song, X Jiang, B Du - ACS nano, 2023 - ACS Publications
Understanding the in vivo transport of nanoparticles provides guidelines for designing
nanomedicines with higher efficacy and fewer side effects. Among many factors, the size of …

Plasmonic photothermal nanoparticles for biomedical applications

M Kim, JH Lee, JM Nam - Advanced Science, 2019 - Wiley Online Library
Recent advances of plasmonic nanoparticles include fascinating developments in the fields
of energy, catalyst chemistry, optics, biotechnology, and medicine. The plasmonic …

Applications and challenges of ultra-small particle size nanoparticles in tumor therapy

J Xu, M Song, Z Fang, L Zheng, X Huang… - Journal of Controlled …, 2023 - Elsevier
With the development of nanotechnology, nanomedicines are widely used in tumor therapy.
However, biological barriers in the delivery of nanoparticles still limit their application in …

[HTML][HTML] The toxicity phenomenon and the related occurrence in metal and metal oxide nanoparticles: a brief review from the biomedical perspective

S Attarilar, J Yang, M Ebrahimi, Q Wang… - … in bioengineering and …, 2020 - frontiersin.org
Thousands of different nanoparticles (NPs) involve in our daily life with various origins from
food, cosmetics, drugs, etc. It is believed that decreasing the size of materials up to …

Effect of physicochemical and surface properties on in vivo fate of drug nanocarriers

Z Zhao, A Ukidve, V Krishnan, S Mitragotri - Advanced drug delivery …, 2019 - Elsevier
Over the years, a plethora of materials–natural and synthetic–have been engineered at a
nanoscopic level and explored for drug delivery. Nanocarriers based on such materials …

Degradability and clearance of silicon, organosilica, silsesquioxane, silica mixed oxide, and mesoporous silica nanoparticles

JG Croissant, Y Fatieiev, NM Khashab - Advanced materials, 2017 - Wiley Online Library
The biorelated degradability and clearance of siliceous nanomaterials have been
questioned worldwide, since they are crucial prerequisites for the successful translation in …

Nanoparticle–liver interactions: Cellular uptake and hepatobiliary elimination

YN Zhang, W Poon, AJ Tavares, ID McGilvray… - Journal of controlled …, 2016 - Elsevier
99% of administered nanoparticles will accumulate and sequester in the liver after
administration into the body. This results in reduced delivery to the targeted diseased tissue …

Nanoparticle uptake: the phagocyte problem

HH Gustafson, D Holt-Casper, DW Grainger… - Nano today, 2015 - Elsevier
Phagocytes are key cellular participants determining important aspects of host exposure to
nanomaterials, initiating clearance, biodistribution and the tenuous balance between host …

[HTML][HTML] Toxicity of nanoparticles and an overview of current experimental models

H Bahadar, F Maqbool, K Niaz… - Iranian biomedical …, 2016 - ncbi.nlm.nih.gov
Nanotechnology is a rapidly growing field having potential applications in many areas.
Nanoparticles (NPs) have been studied for cell toxicity, immunotoxicity, and genotoxicity …

SERS nanoparticles in medicine: from label-free detection to spectroscopic tagging

LA Lane, X Qian, S Nie - Chemical reviews, 2015 - ACS Publications
The development of diagnostic and therapeutic nanoparticles for biomedical applications is
of broad current interest in science, engineering, and medicine. The fundamental basis is …