Advancement in leishmaniasis diagnosis and therapeutics: An update
Leishmaniasis is regarded as a neglected tropical disease by World Health Organization
(WHO) and is ranked next to malaria as the deadliest protozoan disease. The primary …
(WHO) and is ranked next to malaria as the deadliest protozoan disease. The primary …
Host-directed drug therapies for neglected tropical diseases caused by protozoan parasites
The neglected tropical diseases (NTDs) caused by protozoan parasites are responsible for
significant morbidity and mortality worldwide. Current treatments using anti-parasitic drugs …
significant morbidity and mortality worldwide. Current treatments using anti-parasitic drugs …
An appraisal of the scientific current situation and new perspectives in the treatment of cutaneous leishmaniasis
CAB Nieva, AG Cid, AI Romero, MF García-Bustos… - Acta Tropica, 2021 - Elsevier
Abstract Leishmaniasis is a Neglected Tropical Diseases caused by protozoan parasites of
the genus Leishmania. It is a major health problem in many tropical and subtropical regions …
the genus Leishmania. It is a major health problem in many tropical and subtropical regions …
Cutaneous/mucocutaneous leishmaniasis treatment for wound healing: classical versus new treatment approaches
Cutaneous leishmaniasis (CL) and mucocutaneous leishmaniasis (ML) show clinical
spectra that can range from a localized lesion (with a spontaneous healing process) to …
spectra that can range from a localized lesion (with a spontaneous healing process) to …
[HTML][HTML] Potential use of 13-mer peptides based on phospholipase and oligoarginine as leishmanicidal agents
Phospholipase A 2 toxins present in snake venoms interact with biological membranes and
serve as structural models for the design of small peptides with anticancer, antibacterial and …
serve as structural models for the design of small peptides with anticancer, antibacterial and …
Neglected zoonotic diseases: Advances in the development of cell-penetrating and antimicrobial peptides against leishmaniosis and Chagas disease
SM Robledo, S Pérez-Silanes, C Fernández-Rubio… - Pathogens, 2023 - mdpi.com
In 2020, the WHO established the road map for neglected tropical diseases 2021–2030,
which aims to control and eradicate 20 diseases, including leishmaniosis and Chagas …
which aims to control and eradicate 20 diseases, including leishmaniosis and Chagas …
Host-directed therapies for parasitic diseases
B Singh, S Varikuti, G Halsey, G Volpedo… - Future medicinal …, 2019 - Taylor & Francis
Parasitic infections are responsible for significant morbidity and mortality throughout the
world. Management strategies rely primarily on antiparasitic drugs that have side effects and …
world. Management strategies rely primarily on antiparasitic drugs that have side effects and …
Panacea within a Pandora's box: the antiparasitic effects of phospholipases A2 (PLA2s) from snake venoms
Parasitic diseases affect millions of individuals worldwide, mainly in low-income regions.
There is no cure for most of these diseases, and the treatment relies on drugs that have side …
There is no cure for most of these diseases, and the treatment relies on drugs that have side …
Nanotechnology as an alternative to improve the treatment of cutaneous leishmaniasis: A systematic review of the literature
ES De Santana, VB de Souza Belmiro… - Journal of Drug Delivery …, 2022 - Elsevier
Cutaneous leishmaniasis (CL) is a neglected infectious disease caused by the Leishmania
spp parasite and transmitted through the bite of sandflies. Humans are infected by the …
spp parasite and transmitted through the bite of sandflies. Humans are infected by the …
A natural cell-penetrating nanopeptide combined with pentavalent antimonial as experimental therapy against cutaneous leishmaniasis
JRV Silva, NB de Barros, SRA Macedo… - Experimental …, 2020 - Elsevier
The inadequacy of available treatments for leishmaniasis has presented up to 40%
therapeutic failure. This fact suggests an urgency in the discovery of new drugs or alternative …
therapeutic failure. This fact suggests an urgency in the discovery of new drugs or alternative …