Evolutionarily divergent mTOR remodels translatome for tissue regeneration

O Zhulyn, HD Rosenblatt, L Shokat, S Dai… - Nature, 2023 - nature.com
An outstanding mystery in biology is why some species, such as the axolotl, can regenerate
tissues whereas mammals cannot. Here, we demonstrate that rapid activation of protein …

Gradual specialization of phagocytic ameboid cells may have impaired regenerative capacities in metazoan lineages

FMR de Lima, I Abrahão, N Pentagna… - Developmental …, 2023 - Wiley Online Library
Animal regeneration is a fascinating field of research that has captured the attention of many
generations of scientists. Among the cellular mechanisms underlying tissue and organ …

[HTML][HTML] Weak magnetic fields modulate superoxide to control planarian regeneration

LJ Kinsey, AV Van Huizen, WS Beane - Frontiers in Physics, 2023 - frontiersin.org
Reactive oxygen species (ROS) signaling regulates cell behaviors and tissue growth in
development, regeneration, and cancer. Commonly, ROS are modulated pharmacologically …

Cancer in Amphibia, a rare phenomenon?

E Torres‐Dimas, A Cruz‐Ramírez… - Cell Biology …, 2022 - Wiley Online Library
Compared to other animals, the spontaneous occurrence of tumors in wild amphibians is
relatively rare, generally limited to specific populations or species. The number of reports of …

An early Shh–H2O2 reciprocal regulatory interaction controls the regenerative program during zebrafish fin regeneration

M Thauvin, R Matias de Sousa, M Alves… - Journal of cell …, 2022 - journals.biologists.com
Reactive oxygen species (ROS), originally classified as toxic molecules, have attracted
increasing interest given their actions in cell signaling. Hydrogen peroxide (H2O2), the …

The Dynamic Landscapes of Circular RNAs in Axolotl, a Regenerative Medicine Model, with Implications for Early Phase of Limb Regeneration

T Demircan, BE Süzek - OMICS: A Journal of Integrative Biology, 2023 - liebertpub.com
Circular RNAs (circRNAs) are of relevance to regenerative medicine and play crucial roles
in post-transcriptional and translational regulation of biological processes. circRNAs are a …

[HTML][HTML] Post-amputation reactive oxygen species production is necessary for axolotls limb regeneration

B Carbonell-M, J Zapata Cardona… - Frontiers in Cell and …, 2022 - frontiersin.org
Introduction: Reactive oxygen species (ROS) represent molecules of great interest in the
field of regenerative biology since several animal models require their production to promote …

Tail regeneration at different ontogenetic stages of the tiger salamander Ambystoma tigrinum suggests possible changes in regeneration between larval and …

V Bothe, NB Fröbisch - Acta Zoologica, 2023 - Wiley Online Library
Urodele amphibians possess remarkable regenerative abilities, allowing them to rebuild lost
body parts. Contrary to lizards, salamanders can fully restore their tails, including the neural …

[HTML][HTML] Reactive oxygen species: a crosslink between plant and human eukaryotic cell systems

W Guo, Y Xing, X Luo, F Li, M Ren, Y Liang - International Journal of …, 2023 - mdpi.com
Reactive oxygen species (ROS) are important regulating factors that play a dual role in plant
and human cells. As the first messenger response in organisms, ROS coordinate signals in …

[HTML][HTML] Tail and Spinal Cord Regeneration in Urodelean Amphibians

EN Grigoryan, YV Markitantova - Life, 2024 - mdpi.com
Urodelean amphibians can regenerate the tail and the spinal cord (SC) and maintain this
ability throughout their life. This clearly distinguishes these animals from mammals. The …