Silicon-substituted xanthene dyes and their applications in bioimaging

Y Kushida, T Nagano, K Hanaoka - Analyst, 2015 - pubs.rsc.org
Fluorescence imaging is one of the most powerful techniques for visualizing temporal and
spatial changes of biological phenomena in living cells, and many fluorescent probes have …

Small-molecule fluorophores with large Stokes shifts: 9-iminopyronin analogues as clickable tags

P Horváth, P Sebej, T Solomek… - The journal of organic …, 2015 - ACS Publications
The design, synthesis, and both experimental and theoretical studies of several novel 9-
(acylimino)-and 9-(sulfonylimino) pyronin derivatives containing either an oxygen or a …

Near-infrared fluorescent 9-phenylethynylpyronin analogues for bioimaging

T Pastierik, P Sebej, J Medalova… - The Journal of Organic …, 2014 - ACS Publications
The syntheses and biological applications of two novel fluorescent 9-phenylethynylpyronin
analogues containing either carbon or silicon at the position 10 are reported. Both …

FLIM Strategies for Intracellular Sensing: Fluorescence Lifetime Imaging as a Tool to Quantify Analytes of Interest

MJ Ruedas-Rama, JM Alvarez-Pez, L Crovetto… - Advanced Photon …, 2015 - Springer
Since the very early years of microscopy development, scientists have pursued the ability to
observe live cellular activity in order to probe the processes occurring inside cells in real …

A highly fluorescent water soluble spirobifluorene dye with a large Stokes shift: synthesis, characterization and bio-applications

F Schlüter, K Riehemann, NS Kehr, S Quici… - Chemical …, 2018 - pubs.rsc.org
The first water-soluble spirobifluorene derivative has been synthesized, which exhibits high
fluorescence quantum yield and a large Stokes shift (> 100 nm). Proteins induce changes in …

Synthesis and coordination chemistry of a phosphine-decorated fluorescein:“double turn-on” sensing of gold (III) ions in water

AM Christianson, FP Gabbai - Inorganic chemistry, 2016 - ACS Publications
Although phosphine ligands are ubiquitous in transition metal chemistry, few reports of
fluorescent phosphines exist that explore the effect of metal coordination on the …

Divergent synthesis of dihydroxanthene-hemicyanine fused near-infrared fluorophores through the late-stage amination of a bifunctional precursor

MJH Ong, R Srinivasan, A Romieu, JA Richard - Organic letters, 2016 - ACS Publications
A late-stage amination of a bifunctional dihydroxanthene (DHX) scaffold is reported to
access a wide variety of new near-infrared (NIR) chromophores/fluorophores. The divergent …

New dual fluorescent probe for simultaneous biothiol and phosphate bioimaging

S Resa, A Orte, D Miguel, JM Paredes… - … A European Journal, 2015 - Wiley Online Library
The simultaneous detection of relevant metabolites in living organisms by using one
molecule introduces an approach to understanding the relationships between these …

Photophysics of a live-cell-marker, red silicon-substituted xanthene dye

L Crovetto, A Orte, JM Paredes, S Resa… - The Journal of …, 2015 - ACS Publications
Dyes with near-red emission are of great interest because of their undoubted advantages for
use as probes in living cells. In-depth knowledge of their photophysics is essential for …

A solvatofluorochromic silicon-substituted xanthene dye useful in bioimaging

L Espinar-Barranco, P Luque-Navarro, MA Strnad… - Dyes and …, 2019 - Elsevier
In this work, we have performed an in-depth study of the photophysics and
solvatofluorochromism of a red-emitting Si-xanthene dye, an analog of Tokyo Magenta (TM) …