Pathophysiology of IBD associated diarrhea
AN Anbazhagan, S Priyamvada, WA Alrefai… - Tissue …, 2018 - Taylor & Francis
Inflammatory bowel diseases broadly categorized into Crohn's disease (CD) and ulcerative
colitis (UC), are chronic inflammatory disorders of the gastrointestinal tract with increasing …
colitis (UC), are chronic inflammatory disorders of the gastrointestinal tract with increasing …
Mechanisms underlying dysregulation of electrolyte absorption in inflammatory bowel disease–associated diarrhea
S Priyamvada, R Gomes, RK Gill… - Inflammatory bowel …, 2015 - academic.oup.com
Inflammatory bowel diseases (IBDs), including Crohn's disease and ulcerative colitis, are
chronic relapsing inflammatory disorders of the gastrointestinal tract. Chronic inflammation …
chronic relapsing inflammatory disorders of the gastrointestinal tract. Chronic inflammation …
Soluble uric acid increases PDZK1 and ABCG2 expression in human intestinal cell lines via the TLR4-NLRP3 inflammasome and PI3K/Akt signaling pathway
M Chen, X Lu, C Lu, N Shen, Y Jiang, M Chen… - Arthritis research & …, 2018 - Springer
Background In addition to the kidney, the intestine is one of the most important organs
involved in uric acid excretion. However, the mechanism of urate excretion in the intestine …
involved in uric acid excretion. However, the mechanism of urate excretion in the intestine …
Antioxidant and hepatoprotective effect of swertiamarin on carbon tetrachloride-induced hepatotoxicity via the Nrf2/HO-1 pathway
T Wu, J Li, Y Li, H Song - Cellular Physiology and Biochemistry, 2017 - karger.com
Abstract Background/Aims: Swertiamarin (STM), the main bioactive component in Swertia
mussotii Franch (Gentianaceae), has been shown to exert hepatoprotective effects on …
mussotii Franch (Gentianaceae), has been shown to exert hepatoprotective effects on …
Microbial dysbiosis associated with impaired intestinal Na+/H+ exchange accelerates and exacerbates colitis in ex-germ free mice
CA Harrison, D Laubitz, CL Ohland… - Mucosal …, 2018 - nature.com
Intestinal epithelial Na+/H+ exchange facilitated by the apical NHE3 (Slc9a3) is a highly
regulated process inhibited by intestinal pathogens and in inflammatory bowel diseases …
regulated process inhibited by intestinal pathogens and in inflammatory bowel diseases …
The role of plasma membrane sodium/hydrogen exchangers in gastrointestinal functions: proliferation and differentiation, fluid/electrolyte transport and barrier integrity
K Nikolovska, UE Seidler, C Stock - Frontiers in Physiology, 2022 - frontiersin.org
The five plasma membrane Na+/H+ exchanger (NHE) isoforms in the gastrointestinal tract
are characterized by distinct cellular localization, tissue distribution, inhibitor sensitivities …
are characterized by distinct cellular localization, tissue distribution, inhibitor sensitivities …
Slc26 family of anion transporters in the gastrointestinal tract: expression, function, regulation, and role in disease
U Seidler, K Nikolovska - Comprehensive Physiology, 2011 - Wiley Online Library
ABSTRACT SLC26 family members are multifunctional transporters of small anions,
including Cl−, HCO3−, sulfate, oxalate, and formate. Most SLC26 isoforms act as secondary …
including Cl−, HCO3−, sulfate, oxalate, and formate. Most SLC26 isoforms act as secondary …
SLC26A3 (DRA) prevents TNF-alpha-induced barrier dysfunction and dextran sulfate sodium-induced acute colitis
X Ding, D Li, M Li, H Wang, Q He, Y Wang, H Yu… - Laboratory …, 2018 - nature.com
SLC26A3 encodes a Cl−/HCO3− ion transporter that is also known as downregulated in
adenoma (DRA) and is involved in HCO3−/mucus formation. The role of DRA in the …
adenoma (DRA) and is involved in HCO3−/mucus formation. The role of DRA in the …
Role of epithelial ion transports in inflammatory bowel disease
D Magalhaes, JM Cabral… - American Journal of …, 2016 - journals.physiology.org
Inflammatory bowel disease (IBD) is a chronic inflammatory disorder with a complex
pathogenesis. Diarrhea is a highly prevalent and often debilitating symptom of IBD patients …
pathogenesis. Diarrhea is a highly prevalent and often debilitating symptom of IBD patients …
[HTML][HTML] NHERF1 between promises and hopes: overview on cancer and prospective openings
M Centonze, C Saponaro, A Mangia - Translational oncology, 2018 - Elsevier
Na+/H+ exchanger regulatory factor 1 (NHERF1) is a scaffold protein, with two tandem PDZ
domains and a carboxyl-terminal ezrin-binding (EB) region. This particular sticky structure is …
domains and a carboxyl-terminal ezrin-binding (EB) region. This particular sticky structure is …