Figure 3: Three distinctive patterns in mucosal immunopathology occur at either end ofthe
gluten-sensitive spectrum. The'infiltrative'(type 1) lesion, comprising normal crypts and villi …

The intestinal mucosa is physiologically exposed to intense antigenic assaults of dietary and
infectious origins-bacterial, viral, and parasitic. The mucosa is protected by nonimmunologic …

Abstract Background Celiac Disease (CD) is an autoimmune disorder of the small intestine
in which dietary gluten ingestion leads to a chronic enteropathy. Recently, scientific …

Intestinal intraepithelial lymphocytes (IEL) were studied, after isolation in humans for their
surface antigens with a large variety of monoclonal antibodies. They show peculiar …

Introduction Members of the human intestinal microbiota are key players in maintaining
human health. Alterations in the composition of gut microbial community (dysbiosis) have …

The effects of specific nutrients on intestinal maturation and repair after injury are practically
unknown. The purpose of this work was to study the effects of dietary nucleotides on the …

To determine the response of the small intestinal mucosa to environmental conditions, we
studied changes in mucosal architecture and function in a longitudinal cohort study in …

Background: The number of intraepithelial lymphocytes in the duodenum was determined
30 years ago, the suggested normal upper limit being 40 lymphocytes per 100 epithelial …

Studies of the morphologic and phenotypic diversity of intraepithelial T cells in human small
intestine have shown them to be heterogeneous, yet distinct from most extra intestinal T …

In order to identify any dominating subset of activated T cells in the celiac lesion, we
examined CD3+, CD4+, CD8+ and T cell receptor (TcR) γ/δ+ Lymphocytes in jejunal …