Spinal cord injury (SCI) is a life-shattering neurological condition that affects between
250,000 and 500,000 individuals each year with an estimated two to three million people …

Spinal cord injury (SCI) is a central nervous system‐(CNS‐) related disorder for which there
is yet no successful treatment. Within the past several years, cell‐based therapies have …

Acute traumatic spinal cord injury (SCI) results in a devastating loss of neurological function
below the level of injury and adversely affects multiple systems within the body. The …

Over the past 2 decades, advances in understanding the pathophysiology of spinal cord
injury (SCI) have stimulated the recent emergence of several therapeutic strategies that are …

Lipid peroxidation has been reported to play an important role in spinal cord injury (SCI).
Erythropoietin (EPO) is a hematopoietic growth factor that stimulates proliferation and …

Monocyte chemoattractant protein-1 (MCP-1) has been implicated in many inflammatory and
autoimmune diseases. The G-protein-coupled receptor CCR-2B is probably the most …

Innate immunity is part of the early response of the body to deal with tissue damage and
infections. Because of the early nature of the innate immune inflammatory response, this …

Spinal cord injury (SCI) is a devastating neurologic injury with functional deficits for which
the only currently recommended pharmacotherapy is high‐dose methylprednisolone, which …

Traumatic spinal cord injury is frequently associated with brain injury and with alterations in
respiratory and cardiovascular function that require critical care management. Complications …

Rodents are the most widely used species for scientific purposes. A critical pre-requisite of
their use, based on utilitarian ethical reasoning, is the provision of a humane death when …