Genetics of obesity in humans: a clinical review

R Mahmoud, V Kimonis, MG Butler - International journal of molecular …, 2022 - mdpi.com
Obesity is a complex multifactorial disorder with genetic and environmental factors. There is
an increase in the worldwide prevalence of obesity in both developed and developing …

Growth Hormone Research Society workshop summary: consensus guidelines for recombinant human growth hormone therapy in Prader-Willi syndrome

CL Deal, M Tony, C Höybye, DB Allen… - The Journal of …, 2013 - academic.oup.com
Context: Recombinant human GH (rhGH) therapy in Prader-Willi syndrome (PWS) has been
used by the medical community and advocated by parental support groups since its …

Obesity in Prader–Willi syndrome: Physiopathological mechanisms, nutritional and pharmacological approaches

G Muscogiuri, L Barrea, F Faggiano… - Journal of …, 2021 - Springer
Prader–Willi syndrome (PWS) is a genetic disorder caused by the lack of expression of
genes on the paternally inherited chromosome 15q11. 2-q13 region. The three main genetic …

Obesity management in Prader–Willi syndrome: Current perspectives

A Crinò, D Fintini, S Bocchini… - … , metabolic syndrome and …, 2018 - Taylor & Francis
Prader–Willi syndrome (PWS) is a complex multisystem disorder due to the absent
expression of the paternally active genes in the PWS critical region on chromosome 15 …

Liraglutide for weight management in children and adolescents with Prader–Willi syndrome and obesity

G Diene, M Angulo, PM Hale, CH Jepsen… - The Journal of …, 2023 - academic.oup.com
Abstract Context Prader–Willi syndrome (PWS) is characterized by lack of appetite control
and hyperphagia, leading to obesity. Pharmacological options for weight management are …

High prevalence of diabetes mellitus, hypertension and obesity among persons with a recorded diagnosis of intellectual disability or autism spectrum disorder

E Flygare Wallén, G Ljunggren… - Journal of …, 2018 - Wiley Online Library
Background Obesity and lack of physical activity are frequently reported in persons with
intellectual disability (ID) or autism spectrum disorder (ASD). We hypothesised a higher …

[HTML][HTML] Review of Prader-Willi syndrome: the endocrine approach

R Heksch, M Kamboj, K Anglin… - Translational pediatrics, 2017 - ncbi.nlm.nih.gov
Prader-Willi syndrome (PWS) is a complex genetic disorder with implications on the
endocrine and neurologic systems, metabolism, and behavior. Early in life, PWS is …

Prader-Willi syndrome: An uptodate on endocrine and metabolic complications

G Muscogiuri, G Formoso, G Pugliese… - Reviews in Endocrine …, 2019 - Springer
Prader-Willi syndrome (PWS) is a genetic disorder characterized by short stature, low lean
body mass, muscular hypotonia, mental retardation, behavioral abnormalities, dysmorphic …

[HTML][HTML] The consequences of hyperphagia in people with Prader-Willi Syndrome: A systematic review of studies of morbidity and mortality

SA Bellis, I Kuhn, S Adams, L Mullarkey… - European Journal of …, 2022 - Elsevier
Abstract Prader-Willi Syndrome (PWS) is a multi-system genetically determined
neurodevelopmental disorder and the commonest cause of syndromal obesity. The …

[HTML][HTML] Prader-Willi syndrome: endocrine manifestations and management

C Alves, RR Franco - Archives of endocrinology and metabolism, 2020 - SciELO Brasil
Prader-Willi syndrome (PWS) is a genetic disorder caused by the absence of gene
expression in the 15q11. 2-q13 paternal chromosome. Patients with PWS develop …