An overview on target-based drug design against kinetoplastid protozoan infections: Human African trypanosomiasis, Chagas disease and leishmaniases
V Kourbeli, E Chontzopoulou, K Moschovou, D Pavlos… - Molecules, 2021 - mdpi.com
The protozoan diseases Human African Trypanosomiasis (HAT), Chagas disease (CD), and
leishmaniases span worldwide and therefore their impact is a universal concern. The …
leishmaniases span worldwide and therefore their impact is a universal concern. The …
[HTML][HTML] Visceral leishmaniasis: a global overview
RG Wamai, J Kahn, J McGloin, G Ziaggi - Journal of Global Health …, 2020 - e-jghs.org
The leishmaniases are protozoan infections that are among the neglected tropical diseases
(NTDs). Over one billion people are at risk of these diseases in virtually all continents. These …
(NTDs). Over one billion people are at risk of these diseases in virtually all continents. These …
Multifunctional organometallic compounds for the treatment of Chagas disease: Re (i) tricarbonyl compounds with two different bioactive ligands
Chagas' disease (American Trypanosomiasis) is an ancient and endemic illness in Latin
America caused by the protozoan parasite Trypanosoma cruzi. Although there is an urgent …
America caused by the protozoan parasite Trypanosoma cruzi. Although there is an urgent …
Neglected tropical diseases in Brazil: lack of correlation between disease burden, research funding and output
BP Fonseca, PC Albuquerque… - Tropical medicine & …, 2020 - Wiley Online Library
Objectives To assess the correlation between the burden of seven priority neglected tropical
diseases (NTDs) included in the Brazilian National Agenda of Priorities in Health Research …
diseases (NTDs) included in the Brazilian National Agenda of Priorities in Health Research …
Metallomics and other omics approaches in antiparasitic metal-based drug research
Potential use of metal complexes in medicine is an area of bioinorganic chemistry that has
gained much interest. High-throughput omics approaches can provide in-depth insights into …
gained much interest. High-throughput omics approaches can provide in-depth insights into …
Recent progress in the development of indole-based compounds active against malaria, trypanosomiasis and leishmaniasis
PAF Pacheco, MMM Santos - Molecules, 2022 - mdpi.com
Human protozoan diseases represent a serious health problem worldwide, affecting mainly
people in social and economic vulnerability. These diseases have attracted little investment …
people in social and economic vulnerability. These diseases have attracted little investment …
Neglected tropical diseases and systemic racism especially in Brazil: from socio-economic aspects to the development of new drugs
JR da Conceição, CPG Lopes, EI Ferreira, S Epiphanio… - Acta Tropica, 2022 - Elsevier
Neglected tropical diseases (NTDs) are highly prevalent communicable diseases in tropical
and subtropical countries, generally not economically attractive for drug development and …
and subtropical countries, generally not economically attractive for drug development and …
Bestatin analogs-4-quinolinone hybrids as antileishmanial hits: Design, repurposing rational, synthesis, in vitro and in silico studies
Amongst different forms of leishmaniasis, visceral leishmaniasis caused by L. donovani is
highly mortal. Identification of new hit compounds might afford new starting points to develop …
highly mortal. Identification of new hit compounds might afford new starting points to develop …
Facing diseases caused by trypanosomatid parasites: rational design of Pd and Pt complexes with bioactive ligands
D Gambino, L Otero - Frontiers in Chemistry, 2022 - frontiersin.org
Human African Trypanosomiasis (HAT), Chagas disease or American Trypanosomiasis
(CD), and leishmaniases are protozoan infections produced by trypanosomatid parasites …
(CD), and leishmaniases are protozoan infections produced by trypanosomatid parasites …
Marine alkaloids as bioactive agents against protozoal neglected tropical diseases and malaria
AG Tempone, P Pieper, SET Borborema… - Natural product …, 2021 - pubs.rsc.org
Covering: 2000 up to 2021 Natural products are an important resource in drug discovery,
directly or indirectly delivering numerous small molecules for potential development as …
directly or indirectly delivering numerous small molecules for potential development as …