Don't go breakin'my heart: cardioprotective alterations to the mechanical and structural properties of reperfused myocardium during post-infarction inflammation

DP Pearce, MT Nemcek, CM Witzenburg - Biophysical Reviews, 2023 - Springer
Myocardial infarctions (MIs) kickstart an intense inflammatory response resulting in
extracellular matrix (ECM) degradation, wall thinning, and chamber dilation that leaves the …

Physiological Impact of a Synthetic Elastic Protein in Arterial Diseases Related to Alterations of Elastic Fibers: Effect on the Aorta of Elastin-Haploinsufficient Male and …

Q Boëté, M Lo, KL Liu, G Vial, E Lemarié… - International Journal of …, 2022 - mdpi.com
Elastic fibers, made of elastin (90%) and fibrillin-rich microfibrils (10%), are the key
extracellular components, which endow the arteries with elasticity. The alteration of elastic …

Machine learning for automated classification of lung collagen in a urethane-induced lung injury mouse model

KH Alnafisah, A Ranjan, SP Sahu, J Chen… - Biomedical Optics …, 2024 - opg.optica.org
Dysregulation of lung tissue collagen level plays a vital role in understanding how lung
diseases progress. However, traditional scoring methods rely on manual histopathological …

Extracellular Matrix Instability and Chronic Inflammation Underlie Maladaptive Right Ventricular Pressure Overload Remodeling and Failure in Male Mice

I Russo, W Dun, S Mehta, S Ahmed… - American Journal …, 2024 - journals.physiology.org
Right ventricular dysfunction (RVD) portends increased death risk for heart failure (HF) and
pulmonary arterial hypertension (PAH) patients, regardless of left ventricular function or …

[HTML][HTML] Fibrosis quantification using multiphoton excitation imaging of picrosirius red stained cardiac tissue

BA Jones, B Torrado, K Myakala, XX Wang… - Research …, 2023 - ncbi.nlm.nih.gov
Traditional methodologies for fibrosis quantification involve histological measurements,
staining with Masson's trichrome and picrosirius red (PSR), and label-free imaging using …

Etude de l'impact physiologique d'une protéine synthétique élastique dérivée de l'élastine comme signal moléculaire correcteur dans les artériopathies liées aux …

Q Boete - 2022 - theses.hal.science
Les fibres élastiques, composées d'élastine (90%) et de microfibrilles riches en fibrilline
(10%), sont les principaux composants extracellulaires qui confèrent aux artères leur …

[图书][B] Spectrally-Resolved Multiphoton Image Scanning Microscopy of Natural Vascular Scaffolding in Porcine Arterial Walls and Other Biomaterials

T Emeakaroha - 2022 - search.proquest.com
In this work, a custom-built spectrally resolved multiphoton image scanning microscope
system is developed and applied toward characterizing non-invasive vascular scaffolds in …