Identifying novel drugs with new modes of action for neglected tropical fungal skin diseases (fungal skinNTDs) using an Open Source Drug discovery approach

W Lim, A Verbon, W van de Sande - Expert Opinion on Drug …, 2022 - Taylor & Francis
Introduction The three fungal skin neglected tropical diseases (NTD)–mycetoma,
chromoblastomycosis and sporotrichosis–currently lack prioritization and support to …

Potential of the enzyme laccase for the synthesis and derivatization of antimicrobial compounds

V Hahn - World Journal of Microbiology and Biotechnology, 2023 - Springer
Abstract Laccases [EC 1.10. 3.2, benzenediol: dioxygen oxidoreductase] can oxidize
phenolic substances, eg di-and polyphenols, hydroxylated biaryls, aminophenols or …

Sterol biosynthesis inhibitors: C14 demethylation (DMIs)

BN Ziogas, AA Malandrakis - … in Plant Pathogens: Principles and a Guide …, 2015 - Springer
DMIs are a commercially very successful group of systemic fungicides targeting cell
membrane integrity by inhibiting C14 demethylation during sterol formation. Regardless of …

Control efficiency and potential mechanisms of chlorogenic acid against postharvest gray mold caused by Botrytis cinerea on peach fruit

B Dai, Y Wang, H Zhou, L Wang, L Zhou, J Mao… - Postharvest Biology and …, 2024 - Elsevier
Botrytis cinerea (B. cinerea) is characterized by its wide dissemination and high rotting
ability, making peach fruit (Prunus persica L.) highly susceptible to gray mold infection. This …

The biosynthesis of steroids and triterpenoids

GD Brown - Natural Product Reports, 1998 - pubs.rsc.org
2.3. 1 Conversion of lanosterol into cholesterol in animals 2.3. 2 Biosynthesis of steroidal
hormones in vertebrates 2.3. 3 Biosynthesis of vitamin D and bile acids 2.3. 4 Conversion of …

The biochemical mode of action of some newer azole fungicides

IMY Kwok, RT Loeffler - Pesticide science, 1993 - Wiley Online Library
The effects of the newer azole fungicides BAS 480F, flusilazole, and tebuconazole on
growth and sterol composition of the plant pathogenic fungi Botrytis cinerea, Pyrenophora …

Sterols and sphingolipids differentially function in trafficking of the A rabidopsis ABCB 19 auxin transporter

H Yang, GL Richter, X Wang, E Młodzińska… - The Plant …, 2013 - Wiley Online Library
The Arabidopsis ATP‐binding cassette B19 (ABCB 19, P‐glycoprotein19) transporter
functions coordinately with ABCB 1 and PIN 1 to motivate long‐distance transport of the …

[图书][B] Fungicides in practice

RP Oliver, JL Beckerman - 2022 - cabidigitallibrary.org
Fungicide Resistance | Fungicides in Practice Skip the header click to show the menu Menu
Cart Login Login/Register Institutional Access Access Options Enter words / phrases / DOI …

Fenpropimorph slows down the sterol pathway and the development of the arbuscular mycorrhizal fungus Glomus intraradices

E Campagnac, J Fontaine, A Lounès-Hadj Sahraoui… - Mycorrhiza, 2009 - Springer
The direct impact of fenpropimorph on the sterol biosynthesis pathway of Glomus
intraradices when extraradical mycelia alone are in contact with the fungicide was …

Resistance to fenarimol in Nectria haematococca var. cucurbitae

AE Kalamarakis, MA De Waard, BN Ziogas… - Pesticide Biochemistry …, 1991 - Elsevier
Genetic work with 51 fenarimol-selected strains of Nectria haematococca var. cucurbitae
identified a polygenic system for resistance with at least nine chromosomal loci involved …