Comparative efficacy and acceptability of drug treatments for Parkinson's disease with depression: A systematic review with network meta-analysis
XL Wang, ST Feng, YT Wang, B Chen, ZZ Wang… - European Journal of …, 2022 - Elsevier
Depressive symptom is the prevailing non-motor symptom of Parkinson's disease (PD). Drug
treatments for depressed PD (dPD) can mitigate the symptoms of patients. However, the …
treatments for depressed PD (dPD) can mitigate the symptoms of patients. However, the …
Neuroinflammation and L-dopa-induced abnormal involuntary movements in 6-hydroxydopamine-lesioned rat model of Parkinson's disease are counteracted by …
Several lines of evidence have strongly implicated neuroinflammation in Parkinson's
disease (PD) progression and l-dopa-induced dyskinesia. The present study investigated …
disease (PD) progression and l-dopa-induced dyskinesia. The present study investigated …
[HTML][HTML] Broad serotonergic actions of vortioxetine as a promising avenue for the treatment of L-DOPA-induced dyskinesia
Parkinson's Disease (PD) is a neurodegenerative disorder characterized by motor
symptoms that result from loss of nigrostriatal dopamine (DA) cells. While L-DOPA provides …
symptoms that result from loss of nigrostriatal dopamine (DA) cells. While L-DOPA provides …
[HTML][HTML] Serotonin 1A receptor agonist modulation of motor deficits and cortical oscillations by NMDA receptor interaction in parkinsonian rats
X Jiang, P Liang, K Wang, J Jia, X Wang - Neuropharmacology, 2022 - Elsevier
Abstract Although serotonin 1A (5-HT1A) receptor agonists are widely used as the additive
compound to reduce l-dopa-induced dyskinesia in Parkinson's disease (PD), few studies …
compound to reduce l-dopa-induced dyskinesia in Parkinson's disease (PD), few studies …
[HTML][HTML] Multimodal imaging study of the 5-HT1A receptor biased agonist, NLX-112, in a model of L-DOPA-induced dyskinesia
S Chaib, B Vidal, C Bouillot, R Depoortere… - NeuroImage: Clinical, 2023 - Elsevier
Introduction The leading treatment for motor signs of Parkinson's disease is L-DOPA, but,
upon extended use, it can lead to levodopa-induced dyskinesia (LID). Serotonergic neurons …
upon extended use, it can lead to levodopa-induced dyskinesia (LID). Serotonergic neurons …
Purple Carrot Extract Exhibits a Neuroprotective Profile in th e Nigrostriatal Pathway in the Reserpine-induced Model of Parkinson's Disease
AC Custódio-Silva, JIA Beserra-Filho… - … System Agents in …, 2024 - ingentaconnect.com
Background: Parkinson's disease (PD) is a chronic neurodegenerative disorder
characterized by the progressive loss of dopaminergic neurons in the nigrostriatal pathway …
characterized by the progressive loss of dopaminergic neurons in the nigrostriatal pathway …
Different Alterations of Agonist and Antagonist Binding to 5-HT 1A Receptor in a Rat Model of Parkinson's Disease and Levodopa-Induced Dyskinesia: A MicroPET …
B Vidal, E Levigoureux, S Chaib… - Journal of …, 2021 - content.iospress.com
Background: The gold-standard treatment for Parkinson's disease is L-DOPA, which in the
long term often leads to levodopa-induced dyskinesia. Serotonergic neurons are partially …
long term often leads to levodopa-induced dyskinesia. Serotonergic neurons are partially …
Selective Serotonin Reuptake Inhibitors for the Treatment of Depression in Parkinson's Disease: A Systematic Review and Meta-Analysis
R Gao, P Zhao, K Yan - Clinical Drug Investigation, 2024 - Springer
Background Although selective serotonin reuptake inhibitors (SSRIs) are usually considered
safe to use in patients with Parkinson's disease (PD), there are mixed data about their …
safe to use in patients with Parkinson's disease (PD), there are mixed data about their …
Discinesias en la enfermedad de Parkinson, modelación preclínica y alternativas terapéuticas
KCS Llerena, LAF Fonseca… - Revista Cubana de …, 2024 - revfarmacia.sld.cu
Introducción: La discinesia representa la complicación motora más común de la
farmacoterapia con levodopa. La mayoría de los pacientes con Parkinson tienden a …
farmacoterapia con levodopa. La mayoría de los pacientes con Parkinson tienden a …
Kaempferol ameliorated levodopa-induced dyskinesia in experimental rats: A role of brain monoamines, cFOS, FosB, Parkin, Pdyn, TH, and p-JNK.
P Qin, M Liu, X Wang, J Ma - Biocell, 2024 - search.ebscohost.com
Abstract Background: L-dopa (Levodopa) is well known for managing PD (Parkinson's
disease); however, its prolonged use caused dyskinesia (LID). Due to the varied …
disease); however, its prolonged use caused dyskinesia (LID). Due to the varied …