The formation, growth, maintenance, and healing of the skeleton require that bone be
formed throughout life. Normal osteoblasts produce bone under a vanety of conditions …

Bone development requires the recruitment of osteoclast precursors from surrounding
mesenchyme, thereby allowing the key events of bone growth such as marrow cavity …

ABSTRACT A key event in bone resorption is the recruitment of osteoclasts to future
resorption sites. We follow here the migration of preosteoclasts from the periosteum to the …

The osteoclast is the primary bone resorbing cell. It is a highly specialized multinucleated
cell whose primary function is to help in the control of calcium homeostasis. The osteoclast …

Bisphosphonates are now widely used in the treatment of bone diseases, particularly where
there is uncontrolled bone resorption, as they are known to be potent inhibitors of …

Background Articular cartilage is an extremely specialized connective tissue which covers
all diarthrodial joints. Implantation of chondrogenic cells without or with additional …

We retrospectively studied the incidence of primary surgical revision for stump overgrowth in
a population of childhood and adolescent amputees. The anatomic location and the etiology …

Although 14-day-old mouse embryonic calvarial cells cultured in plastic culture dishes in the
presence of 1α, 25-dihydroxyvitamin D 3 [1α, 25-(OH) 2 D 3] for 7 days could barely resorb …

To investigate the functional stages of osteoclasts, the ultrastructural histochemical
distribution of the lysosomal enzymes [acid phosphatase (tartrate‐sensitive) and neutral …

Osteoblasts are involved in the bone resorption process by regulating osteoclast maturation
and activity. In order to elucidate the mechanisms underlying osteoblast/preosteoclast cell …