Infection with the human immunodeficiency virus (HIV) results in a profound
immunosuppression due predominantly to a selective depletion of helper/inducer T …

Interactions between the viral envelope glycoprotein gp120 and the cell surface receptor
CD4 are responsible for the entry of human immunodeficiency virus type 1 (HIV-1) into host …

Mineralocorticoid receptors, both when in tissue extracts and when recombinant-derived,
have equal affinity for the physiological mineralocorticoid aldosterone and for the …

The CD4 (T4) antigen is a cell-surface glycoprotein that is expressed predominantly on the
surface of helper T cells and has been implicated in the regulation of T-cell activation and in …

Hypercholesterolemia is a major risk factor for development of atherosclerosis. In
experimental animals fed a high-cholesterol diet, monocytes adhere to the arterial …

Monocytes and macrophages, which may play a central role in the pathogenesis of infection
with human immunodeficiency virus type 1 (HIV-1), express the CD4 molecule and Fc …

We describe a novel nucleoside analog, 2'-deoxy-3'-thiacytidine (BCH-189), in which the
3'carbon of the ribose ring of 2'-deoxycytidine has been replaced by a sulfur atom. In MT-4 T …

Retroviruses (without transforming genes) are thought to cause leukemias and other
cancers in animals and humans because they were originally isolated from those diseases …

T-cell acute lymphoblastic leukemia (T-ALL), a T-cell malignant disease that mainly affects
children, is still a medical challenge, especially for refractory patients for whom therapeutic …

The distribution, function and ontogeny of the mononuclear phagocyte system of the chicken
were characterised using the monoclonal antibody (MAb) KUL01. KUL01 specifically …