In a normal human life span, the heart beats about 2–3 billion times. Under diseased
conditions, a heart may lose its normal rhythm and degenerate suddenly into much faster …

The use of cardiovascular implantable electronic devices (CIEDs) has proved to be the most
successful device‐based therapy to reduce morbidity and mortality of cardiovascular …

Controlling the complex spatio-temporal dynamics underlying life-threatening cardiac
arrhythmias such as fibrillation is extremely difficult, because of the nonlinear interaction of …

The self-organized dynamics of vortex-like rotating waves, which are also known as scroll
waves, are the basis of the formation of complex spatiotemporal patterns in many excitable …

The global burden caused by cardiovascular disease is substantial, with heart disease
representing the most common cause of death around the world. There remains a need to …

This review article gives a comprehensive survey of the progress made in computational
modeling of the human atria during the last 10 years. Modeling the anatomy has emerged …

Alternans of action potential duration has been associated with T wave alternans and the
development of arrhythmias because it produces large gradients of repolarization. However …

The development of new approaches to control cardiac arrhythmias requires a deep
understanding of spiral wave dynamics. Optogenetics offers new possibilities for this …

The beating of the heart is a synchronized contraction of muscle cells (myocytes) that is
triggered by a periodic sequence of electrical waves (action potentials) originating in the …

A normal heartbeat is orchestrated by the stable propagation of an excitation wave that
produces an orderly contraction. In contrast, wave turbulence in the ventricles, clinically …