Cardiovascular disease is a leading cause of death, and translational research is needed to
understand better mechanisms whereby the left ventricle responds to injury. Mouse models …

Vitamin A is an essential nutrient required throughout life. Through its various metabolites,
vitamin A sustains fetal development, immunity, vision, and the maintenance, regulation, and …

While the uses of retinoids for cancer treatment continue to evolve, this review focuses on
other therapeutic areas in which retinoids [retinol (vitamin A), all-trans retinoic acid (RA), and …

The vitamin A metabolite, retinoic acid, is an important signaling molecule during embryonic
development serving critical roles in morphogenesis, organ patterning and skeletal and …

Background & Aims The small intestine (SI) displays regionality in nutrient and
immunological function. Following SI tissue loss (as occurs in short gut syndrome, or SGS) …

The nutritional requirements of the developing embryo are complex. In the case of dietary
vitamin A (retinol, retinyl esters and provitamin A carotenoids), maternal derived nutrients …

Background Perturbed mitochondrial energetics and vitamin A (VitA) metabolism are
associated with the pathogenesis of diet-induced obesity (DIO) and type 2 diabetes (T2D) …

Perturbed vitamin-A metabolism is associated with type 2 diabetes and mitochondrial
dysfunction that are pathophysiologically linked to the development of diabetic …

The main active metabolite of Vitamin A, all-trans retinoic acid (RA), is required for proper
cellular function and tissue organization. Heart development has a well-defined requirement …

The importance of fat-soluble vitamin A in the body is well known and recognized. Vitamin A
is the term used for a group of fat-soluble nutrients, such as retinal, retinol, and retinyl esters …