Glucose is the long-established, obligatory fuel for brain that fulfills many critical functions,
including ATP production, oxidative stress management, and synthesis of neurotransmitters …

Inflammation is a complex biological response fundamental to how the body deals with
injury and infection to eliminate the initial cause of cell injury and effect repair. Unlike a …

Healthy aging is an ambitious aspiration for humans, but neurodegenerative disorders, such
as Alzheimer's disease (AD), strongly affect quality of life. Using an integrated omics …

Free d-amino acids (d-AAs) are emerging as a novel and important class of signaling
molecules in many organs, including the brain and endocrine systems. There has been …

The perspective of neuroinflammation as an epiphenomenon following neuron damage is
being replaced by the awareness of glia and their importance in neural functions and …

Abstracts Background D-amino acids have been recognized as bioactive substances in
humans. d-Serine and D-alanine are co-agonists of N-methyl-d-aspartate receptors …

Abstract d-Serine acts as a co-agonist of N-methyl-d-aspartate receptors (NMDAR) which
appear overactivated in AD, while d-aspartate is a modulatory molecule acting on NMDAR …

D-amino acids have been known to exist in the human brain for nearly 40 years, and they
continue to be a field of active study to today. This review article aims to give a concise …

Abstract Alzheimer's disease (AD), the main cause of dementia worldwide, is characterized
by a complex and multifactorial etiology. In large part, excitatory neurotransmission in the …

Amino acids are important components for peptides and proteins and act as signal
transmitters. Only L‐amino acids have been considered necessary in mammals, including …