Chemotherapy has significantly increased the number of cancer survivors. However,
chemotherapy itself carries various adverse effects that limit the efficacy of treatment and …

Intramedullary tumors are rare, accounting for only about 4% of all CNS neoplasms.
Although surgery represents the most effective treatment, recurrence may occur. As a large …

A retrospective analysis has been made of all patients with pineal and CNS germ cell tumors
who were treated at the Royal Marsden Hospital between 1962–1987. A total of 67 new …

Twenty-five patients with CNS metastases of choriocarcinoma were treated with a regimen
incorporating etoposide, methotrexate, and actinomycin (EMA) alternating weekly with …

Gefitinib is active and well tolerated in patients with advanced non-small cell lung cancer
(NSCLC); however, its role in patients with brain metastases has not been clearly defined …

PURPOSE Despite improved cure rates for patients with metastatic testicular cancer with
cisplatin-based combination chemotherapy, patients who develop brain metastases are …

BACKGROUND Multiinstitutional experience with the management of cerebral metastases
from malignant germ cell tumors (MGCT) is presented. METHODS Clinical data regarding …

Fourteen patients with brain metastases from previously untreated small-cell lung cancer
(SCLC) were treated with three courses of systemic chemotherapy as an initial mode of …

Background An alternating combination chemotherapy schedule for advanced
nonseminomatous germ cell tumours (NSGCT) has been in use since 1977. Patients and …

This study evaluated the clinical and radiological characteristics, as well as the treatment
outcomes, for the rare phenomenon known as intracranial growing teratoma syndrome …