GABA tone regulation and its cognitive functions in the brain
Abstract γ-Aminobutyric acid (GABA) is the major inhibitory neurotransmitter released at
GABAergic synapses, mediating fast-acting phasic inhibition. Emerging lines of evidence …
GABAergic synapses, mediating fast-acting phasic inhibition. Emerging lines of evidence …
GABAergic interneurons in the neocortex: from cellular properties to circuits
Cortical networks are composed of glutamatergic excitatory projection neurons and local
GABAergic inhibitory interneurons that gate signal flow and sculpt network dynamics …
GABAergic inhibitory interneurons that gate signal flow and sculpt network dynamics …
[HTML][HTML] Less is more: expectation sharpens representations in the primary visual cortex
Prior expectations about the visual world facilitate perception by allowing us to quickly
deduce plausible interpretations from noisy and ambiguous data. The neural mechanisms of …
deduce plausible interpretations from noisy and ambiguous data. The neural mechanisms of …
Deep cortical layers are activated directly by thalamus
CM Constantinople, RM Bruno - Science, 2013 - science.org
The thalamocortical (TC) projection to layer 4 (L4) is thought to be the main route by which
sensory organs communicate with cortex. Sensory information is believed to then propagate …
sensory organs communicate with cortex. Sensory information is believed to then propagate …
Tracking neural activity from the same cells during the entire adult life of mice
S Zhao, X Tang, W Tian, S Partarrieu, R Liu… - Nature …, 2023 - nature.com
Stably recording the electrical activity of the same neurons over the adult life of an animal is
important to neuroscience research and biomedical applications. Current implantable …
important to neuroscience research and biomedical applications. Current implantable …
Dynamic lateralization of pupil dilation evoked by locus coeruleus activation results from sympathetic, not parasympathetic, contributions
Pupil size is collectively controlled by the sympathetic dilator and parasympathetic sphincter
muscles. Locus coeruleus (LC) activation has been shown to evoke pupil dilation, but how …
muscles. Locus coeruleus (LC) activation has been shown to evoke pupil dilation, but how …
[HTML][HTML] Barrel cortex function
D Feldmeyer, M Brecht, F Helmchen… - Progress in …, 2013 - Elsevier
Neocortex, the neuronal structure at the base of the remarkable cognitive skills of mammals,
is a layered sheet of neuronal tissue composed of juxtaposed and interconnected columns …
is a layered sheet of neuronal tissue composed of juxtaposed and interconnected columns …
Moving sensory adaptation beyond suppressive effects in single neurons
SG Solomon, A Kohn - Current biology, 2014 - cell.com
How an object is perceived depends on the temporal context in which it is encountered.
Sensory signals in the brain also depend on temporal context, a phenomenon often referred …
Sensory signals in the brain also depend on temporal context, a phenomenon often referred …
The impact of chronic blood–brain barrier breach on intracortical electrode function
Brain-computer interfaces (BCIs) have allowed control of prosthetic limbs in paralyzed
patients. Unfortunately, the electrodes of the BCI that interface with the brain only function for …
patients. Unfortunately, the electrodes of the BCI that interface with the brain only function for …
Astrocytes control sensory acuity via tonic inhibition in the thalamus
Sensory discrimination is essential for survival. However, how sensory information is finely
controlled in the brain is not well defined. Here, we show that astrocytes control tactile acuity …
controlled in the brain is not well defined. Here, we show that astrocytes control tactile acuity …