Activation of the interleukin-23/interleukin-17 signalling pathway in autoinflammatory and autoimmune uveitis

Z Zhong, G Su, A Kijlstra, P Yang - Progress in retinal and eye research, 2021 - Elsevier
Uveitis is a group of diseases characterized by intraocular inflammation, of which some are
driven by autoinflammatory or autoimmune responses, such as Vogt-Koyanagi-Harada …

Practical significance of biomarkers in axial spondyloarthritis: updates on diagnosis, disease activity, and prognosis

AD Diaconu, A Ceasovschih, V Șorodoc… - International journal of …, 2022 - mdpi.com
Axial spondyloarthritis (axSpA) is a chronic inflammatory disease that can lead to ankylosis
by secondary ossification of inflammatory lesions, with progressive disability and a …

Common genetic variants and pathways in diabetes and associated complications and vulnerability of populations with different ethnic origins

SS Shoily, T Ahsan, K Fatema, AA Sajib - Scientific Reports, 2021 - nature.com
Diabetes mellitus is a complex and heterogeneous metabolic disorder which is often pre-or
post-existent with complications such as cardiovascular disease, hypertension …

Influence of IL10 (rs1800896) Polymorphism and TNF-α, IL-10, IL-17A, and IL-17F Serum Levels in Ankylosing Spondylitis

M Braga, FF Lara-Armi, JSF Neves… - Frontiers in …, 2021 - frontiersin.org
Ankylosing spondylitis (AS) is a chronic autoimmune inflammatory disease that mainly
affects the axial and sacroiliac joints. Single-nucleotide polymorphisms (SNPs) in genes …

Integrative single-cell RNA-seq and ATAC-seq analysis of peripheral mononuclear cells in patients with ankylosing spondylitis

H Xu, H Yu, L Liu, H Wu, C Zhang, W Cai… - Frontiers in …, 2021 - frontiersin.org
Objective Genetic studies on ankylosing spondylitis (AS) have identified more than 100
pathogenic genes. Building a bridge between these genes and biologically targeted …

Punicalagin Exerts Protective Effects against Ankylosing Spondylitis by Regulating NF‐κB‐TH17/JAK2/STAT3 Signaling and Oxidative Stress

X Feng, Q Yang, C Wang, W Tong… - BioMed Research …, 2020 - Wiley Online Library
Background. Ankylosing spondylitis (AS) is a chronic inflammatory disease characterized by
sacroiliitis and spinal rigidity of the axial joints. The role of oxidative stress and increased …

Tumor necrosis factor alpha-308G/A gene polymorphisms combined with neutrophil-to-lymphocyte and platelet-to-lymphocyte ratio predicts the efficacy and safety of …

Z Wang, L Kong, H Zhang, F Sun, Z Guo… - Frontiers in …, 2022 - frontiersin.org
Background: TNF-α has been reported to be closely associated with autoimmune
inflammatory diseases. This study aims to investigate the role of TNF-α-308 (rs1800629) G/A …

FABP5 enhances malignancies of lower‐grade gliomas via canonical activation of NF‐κB signaling

Y Wang, A Wahafu, W Wu, J Xiang… - Journal of cellular …, 2021 - Wiley Online Library
Low‐grade gliomas (LGGs) are grade III gliomas based on the WHO classification with
significant genetic heterogeneity and clinical properties. Traditional histological …

A review article of inflammatory bowel disease treatment and pharmacogenomics

N Eltantawy, IAEH El-Zayyadi, AA Elberry… - Beni-Suef University …, 2023 - Springer
Inflammatory bowel disease (IBD) involves a variety of conditions, particularly Crohn's
disease (CD) and ulcerative colitis (UC). IBD is characterized by chronic inflammatory …

Association between IL-17A and IL-17F gene polymorphism and susceptibility in inflammatory arthritis: A meta-analysis

M Shao, S Xu, H Yang, W Xu, J Deng, Y Chen, X Gao… - Clinical …, 2020 - Elsevier
Abstract Objectives The association between Interleukin (IL)-17A and IL-17F gene
polymorphism with inflammatory arthritis were inconsistent among previous studies. This …