The role of Bcl-2 family member BNIP3 in cell death and disease: NIPping at the heels of cell death

TR Burton, SB Gibson - Cell Death & Differentiation, 2009 - nature.com
Bcl-2 nineteen-kilodalton interacting protein (BNIP3) is a BH-3-only Bcl-2 family member
whose expression levels increase during stress such as hypoxia through hypoxia-inducing …

The polymorphic and contradictory aspects of intermittent hypoxia

I Almendros, Y Wang, D Gozal - American Journal of …, 2014 - journals.physiology.org
Intermittent hypoxia (IH) has been extensively studied during the last decade, primarily as a
surrogate model of sleep apnea. However, IH is a much more pervasive phenomenon in …

[HTML][HTML] The effect of eight weeks resistance and endurance training on some angiogenesis factors of hippocampus tissue in male wistar rats

M Sadegh Ghomi, M Kashef… - Journal of Sport and …, 2021 - joeppa.sbu.ac.ir
Purpose: One of the cause of adaptations due to exercise training is increased capillary
density or angiogenesis. increased blood flow to hippocampus tissue causes improvement …

مقایسة اثر تمرین تناوبی شدید و مقاومتی فزاینده بر بیان ژن ATF3 عضلة قلبی موش‌های صحرایی دیابتی نر

سفال منش, شهاب الدین, خالدی, ندا, رجبی… - نشریه فیزیولوژی ورزش و …, 2021‎ - joeppa.sbu.ac.ir
هدف: از سازوکارهای مؤثر در انجام بهتر عملکرد عضلانی در ورزشکاران، القای ظرفیت
پیش‌فعال‌سازی (PAP) در روش گرم کردن است. ازاین‌رو، پژوهش حاضر به‌منظور بررسی تأثیر گرم …

Synergistic effect of HIF‐1α and FoxO3a trigger cardiomyocyte apoptosis under hyperglycemic ischemia condition

YF Chen, S Pandey, CH Day, YF Chen… - Journal of Cellular …, 2018 - Wiley Online Library
Cardiomyocyte death is an important pathogenic feature of ischemia and heart failure.
Through this study, we showed the synergistic role of HIF‐1α and FoxO3a in cardiomyocyte …

Andrographis paniculata extract attenuates pathological cardiac hypertrophy and apoptosis in high-fat diet fed mice

YL Hsieh, MA Shibu, CK Lii, VP Viswanadha… - Journal of …, 2016 - Elsevier
Abstract Ethnopharmacological relevance Andrographis paniculata (Burm. f.) Nees
(Acanthaceae) has a considerable medicinal reputation in most parts of Asia as a potent …

Hypoxia suppresses myocardial survival pathway through HIF-1α-IGFBP-3-dependent signaling and enhances cardiomyocyte autophagic and apoptotic effects mainly …

CC Feng, CC Lin, YP Lai, TS Chen… - Growth …, 2016 - Taylor & Francis
The HIF-1α transcriptional factor and the BH-3 only protein BNIP3 are known to play
fundamental roles in response to hypoxia. The objective of this research is to investigate the …

Cellular apoptosis and cardiac dysfunction in STZ‐induced diabetic rats attenuated by anthocyanins via activation of IGFI‐R/PI3K/Akt survival signaling

PC Huang, GJ Wang, MJ Fan… - Environmental …, 2017 - Wiley Online Library
Anthocyanins are known cyto‐protective agents against various stress conditions. In this
study cardio‐protective effect of anthocyanins from black rice against diabetic mellitus (DM) …

Effects of 17beta‐estradiol on cardiac apoptosis in ovariectomized rats

CM Liou, AL Yang, CH Kuo, H Tin… - Cell biochemistry …, 2010 - Wiley Online Library
Objectives Cardiac apoptosis was found in ovariectomized rats without ischemia. Limited
information regarding the protective effects of 17β‐estradiol (E2) on cardiac Fas‐dependent …

Andrographolide mitigates cardiac apoptosis to provide cardio‐protection in high‐fat‐diet‐induced obese mice

KH Lin, S Marthandam Asokan, WW Kuo… - Environmental …, 2020 - Wiley Online Library
Excessive intake of high fat diet (HFD) and associated obese conditions are critical
contributors of cardiac diseases. In this study, an active metabolite andrographolide from …