Most of the phylogenetic diversity of life is found in bacteria and archaea, and is reflected in
the diverse metabolism and functions of bacterial and archaeal polyamines. The polyamine …

L-asparaginase (L-ASNase) is a vital enzyme with a broad range of applications in
medicine, food industry, and diagnostics. Among various organisms expressing L-ASNases …

Complex functioning of the genome in the cell nucleus is controlled at different levels:(a) the
DNA base sequence containing all relevant inherited information;(b) epigenetic pathways …

Polyamines (PAs) are important molecules that determine cell longevity or death. Studies
have shown that nutritional supplementation with spermidine can reduce age-related …

Nucleic acid delivery to cells is an important therapeutic strategy that requires the transport
of nucleic acids to intracellular compartments and their protection from enzymatic …

Polyamines (PAs) are positively charged amines such as putrescine, spermidine and
spermine that ubiquitously exist in all organisms. They have been considered as a new type …

The history of polyamines dates back to the fifteenth century when spermine was discovered
by Antonie van Leeuwenhoek [born in Delft, Holland (1632–1723)], but it took several …

Polyamines are involved in various biological functions, including cell proliferation,
differentiation, gene regulation, etc. Recently, it was found that polyamines exhibit biphasic …

Background It is becoming clearer that living cells use water/water (w/w) phase separation to
form membraneless organelles that exhibit various important biological functions. Currently …

Cell-free gene expression systems have been valuable tools for understanding how
transcription/translation can be regulated in living cells. Many studies have investigated the …