[HTML][HTML] Non-targeted analysis (NTA) and suspect screening analysis (SSA): a review of examining the chemical exposome

KE Manz, A Feerick, JM Braun, YL Feng… - Journal of exposure …, 2023 - nature.com
Non-targeted analysis (NTA) and suspect screening analysis (SSA) are powerful techniques
that rely on high-resolution mass spectrometry (HRMS) and computational tools to detect …

[HTML][HTML] Metabolomics in environmental toxicology: Applications and challenges

C Bedia - Trends in Environmental Analytical Chemistry, 2022 - Elsevier
Metabolomics is a discipline aiming to characterize the presence of metabolites in biological
matrices under specific conditions. In recent years, metabolomics has increasingly been …

CFM-ID 4.0–a web server for accurate MS-based metabolite identification

F Wang, D Allen, S Tian, E Oler, V Gautam… - Nucleic acids …, 2022 - academic.oup.com
Abstract The CFM-ID 4.0 web server (https://cfmid. wishartlab. com) is an online tool for
predicting, annotating and interpreting tandem mass (MS/MS) spectra of small molecules. It …

[HTML][HTML] Understanding the chemical exposome during fetal development and early childhood: a review

M Krausová, D Braun… - Annual Review of …, 2023 - annualreviews.org
Early human life is considered a critical window of susceptibility to external exposures.
Infants are exposed to a multitude of environmental factors, collectively referred to as the …

CIL-ExPMRM: An Ultrasensitive Chemical Isotope Labeling Assisted Pseudo-MRM Platform to Accelerate Exposomic Suspect Screening

J Zheng, J Yang, F Zhao, B Peng… - … Science & Technology, 2023 - ACS Publications
Exposome is the future of next-generation environmental health to establish the association
between environmental exposure and diseases. However, due to low concentrations of …

Harmonized quality assurance/quality control provisions for nontargeted measurement of urinary pesticide biomarkers in the HBM4EU multisite SPECIMEn study

CM Vitale, A Lommen, C Huber, K Wagner… - Analytical …, 2022 - ACS Publications
A set of quality assurance/quality control (QA/QC) criteria for nontargeted measurement of
pesticide exposure markers in a large-scale study of human urine has been proposed and …

[HTML][HTML] Insights into the early-life chemical exposome of Nigerian infants and potential correlations with the developing gut microbiome

I Oesterle, KI Ayeni, CN Ezekiel, D Berry… - Environment …, 2024 - Elsevier
Early-life exposure to natural and synthetic chemicals can impact acute and chronic health
conditions. Here, a suspect screening workflow anchored on high-resolution mass …

[HTML][HTML] What is in the fish? Collaborative trial in suspect and non-target screening of organic micropollutants using LC-and GC-HRMS

W Dürig, S Lindblad, O Golovko, G Gkotsis… - Environment …, 2023 - Elsevier
A collaborative trial involving 16 participants from nine European countries was conducted
within the NORMAN network in efforts to harmonise suspect and non-target screening of …

[HTML][HTML] Innovative analytical methodologies for characterizing chemical exposure with a view to next-generation risk assessment

Ž Tkalec, JP Antignac, N Bandow, FM Béen… - Environment …, 2024 - Elsevier
The chemical burden on the environment and human population is increasing.
Consequently, regulatory risk assessment must keep pace to manage, reduce, and prevent …

Analytical strategies to profile the internal chemical exposome and the metabolome of human placenta

R Al-Salhi, C Monfort, N Bonvallot, A David - Analytica Chimica Acta, 2022 - Elsevier
As a non-invasive biological matrix, the placenta offers great and novel opportunities to
monitor fetal exposure to exogenous chemicals and their biotransformation products (the …