Atrial fibrillation is a common heart rhythm disorder that leads to an increased risk for stroke
and heart failure. Atrial fibrillation is a complex disease with both environmental and genetic …

Atrial fibrillation (AF) is the most common arrhythmia with ever-increasing public health
impact. 1 Over 50 years of observation in the Framingham Heart Study (FHS), there is a 4 …

To identify genetic variation underlying atrial fibrillation, the most common cardiac
arrhythmia, we performed a genome-wide association study of> 1,000,000 people, including …

Genome-wide association studies (GWAS) have identified thousands of genetic variants
linked to the risk of human disease. However, GWAS have so far remained largely …

Importance Early-onset atrial fibrillation (AF) can be the initial manifestation of a more
serious underlying inherited cardiomyopathy or arrhythmia syndrome. Objective To examine …

Importance Atrial fibrillation (AF) can develop following thoracic irradiation. However, the
critical cardiac substructure responsible for AF has not been properly studied. Objective To …

Aortic valve stenosis (AS) is the most common valvular heart disease, and valve
replacement is the only definitive treatment. Here we report a large genome-wide …

The electrocardiographic PR interval reflects atrioventricular conduction, and is associated
with conduction abnormalities, pacemaker implantation, atrial fibrillation (AF), and …

Atrial fibrillation (AF) is the most common type of arrhythmia. Epidemiological studies have
documented a substantial genetic component. More than 160 genes have been associated …

Importance Although rare variants in cardiac ion channels, transcription factors, and
myocardial structural proteins are associated with early-onset atrial fibrillation (AF) in White …