That adult humans possess active brown adipose tissue potentially leads to a paradigm shift
in the understanding of human metabolism and of obesity. Adaptive adrenergic …

Excessive fat accumulation in the body causes overweight and obesity. To date, research
has confirmed that there are two types of adipose tissue with opposing functions: lipid …

AACE= American Association of Clinical Endocrinologists; AAES= American Association of
Endocrine Surgeons; ACC= adrenocortical carcinoma; ACE= angiotensin-converting …

Context: Ectopic ACTH secretion (EAS) is difficult to diagnose and treat. We present our
experience with EAS from 1983 to 2004. Setting: The study was performed at a tertiary care …

Genes are transcribed in a discontinuous pattern referred to as RNA bursting, but the
mechanisms regulating this process are unclear. Although many physiological signals …

Cushing disease is caused by a corticotroph tumor of the pituitary gland. Patients with
Cushing disease are usually treated with transsphenoidal surgery, as this approach leads to …

Abstract Context: The diagnosis of Cushing's syndrome (CS) requires the use of tests of
unregulated hypercortisolism that have unclear accuracy. Objective: Our objective was to …

Objective: Neuroendocrine–immune models have been proposed to account for the frequent
co-occurrence of pain, depression, and fatigue (PDF) among cancer patients. Design: In a …

Glucocorticoids are involved in several responses triggered by a variety of environmental
and physiological stimuli. These hormones have a wide-range of regulatory effects in …

Cushing's disease (CD) is rare in paediatric practice but requires prompt investigation,
diagnosis and therapy to prevent long-term complications. Key presenting features are a …