Emerging strategies in developing multifunctional nanomaterials for cancer nanotheranostics
Cancer involves a collection of diseases with a common trait–dysregulation in cell
proliferation. At present, traditional therapeutic strategies against cancer have limitations in …
proliferation. At present, traditional therapeutic strategies against cancer have limitations in …
Near-infrared light-initiated molecular superoxide radical generator: rejuvenating photodynamic therapy against hypoxic tumors
M Li, J Xia, R Tian, J Wang, J Fan, J Du… - Journal of the …, 2018 - ACS Publications
Hypoxia, a quite universal feature in most solid tumors, has been considered as the
“Achilles' heel” of traditional photodynamic therapy (PDT) and substantially impairs the …
“Achilles' heel” of traditional photodynamic therapy (PDT) and substantially impairs the …
Superoxide radical photogenerator with amplification effect: surmounting the achilles' heels of photodynamic oncotherapy
M Li, T Xiong, J Du, R Tian, M Xiao, L Guo… - Journal of the …, 2019 - ACS Publications
Strong oxygen dependence, poor tumor targeting, and limited treatment depth have been
considered as the “Achilles' heels” facing the clinical usage of photodynamic therapy (PDT) …
considered as the “Achilles' heels” facing the clinical usage of photodynamic therapy (PDT) …
Drug delivery systems for photodynamic therapy: the potentiality and versatility of electrospun nanofibers
SM Costa, R Fangueiro… - Macromolecular …, 2022 - Wiley Online Library
Recently, photodynamic therapy (PDT) has become a promising approach for the treatment
of a broad range of diseases, including oncological and infectious diseases. This minimally …
of a broad range of diseases, including oncological and infectious diseases. This minimally …
[HTML][HTML] Current targets and bioconjugation strategies in photodynamic diagnosis and therapy of cancer
S Gomez, A Tsung, Z Hu - Molecules, 2020 - mdpi.com
Photodynamic diagnosis (PDD) and therapy (PDT) are emerging, non/minimally invasive
techniques for cancer diagnosis and treatment. Both techniques require a photosensitizer …
techniques for cancer diagnosis and treatment. Both techniques require a photosensitizer …
Increasing cancer permeability by photodynamic priming: from microenvironment to mechanotransduction signaling
NM Carigga Gutierrez, N Pujol-Solé, Q Arifi… - Cancer and Metastasis …, 2022 - Springer
The dense cancer microenvironment is a significant barrier that limits the penetration of
anticancer agents, thereby restraining the efficacy of molecular and nanoscale cancer …
anticancer agents, thereby restraining the efficacy of molecular and nanoscale cancer …
“Click” for precise photodynamic therapy
LKB Tam, DKP Ng - Materials Chemistry Frontiers, 2023 - pubs.rsc.org
Bioorthogonal chemistry has been a powerful tool in chemical biology. It can facilitate the
study of biomolecules in their native environments and enables targeted delivery and …
study of biomolecules in their native environments and enables targeted delivery and …
Remotely Phototriggered, Transferrin‐Targeted Polymeric Nanoparticles for the Treatment of Breast Cancer
R Jadia, J Kydd, P Rai - Photochemistry and photobiology, 2018 - Wiley Online Library
Triple‐negative breast cancer (TNBC) has the worst prognosis among all subtypes of breast
cancer. Currently, no targeted treatment has been approved for TNBC. The goal of this study …
cancer. Currently, no targeted treatment has been approved for TNBC. The goal of this study …
[HTML][HTML] Near-infrared pH-switchable BODIPY photosensitizers for dual biotin/cRGD targeted photodynamic therapy
M Porubský, J Hodoň, J Stanková, P Džubák… - … of Photochemistry and …, 2024 - Elsevier
Photodynamic therapy (PDT) is a clinically-approved cancer treatment that is based on
production of cytotoxic reactive oxygen species to induce cell death. However, its efficiency …
production of cytotoxic reactive oxygen species to induce cell death. However, its efficiency …
[HTML][HTML] Computational modelling of the therapeutic outputs of photodynamic therapy on spheroid-on-chip models
H Kazempour, F Teymouri, M Khatami… - … of Photochemistry and …, 2024 - Elsevier
Photodynamic therapy (PDT) is a medical radio chemotherapeutic method that uses light,
photosensitizing agents, and oxygen to produce cytotoxic compounds, which eliminate …
photosensitizing agents, and oxygen to produce cytotoxic compounds, which eliminate …