The human genome encodes nine different adrenoceptor genes. These are grouped into
three families, namely, the α 1-, α 2-, and β-adrenoceptors, with three family members each …

The β 3-adrenergic receptor (β 3-AR) is an important regulator of various physiological
functions, such as thermogenesis in brown adipose tissue, lipolysis in white adipose tissue …

As obesity has become a major global public health challenge, a large number of studies
have analyzed different strategies aimed at inducing a negative energy balance and …

Background In some populations, obesity and body weight related disorders show a
correlation with polymorphisms in three subtypes of beta-adrenoceptor (β1, β2, and …

Objectives: Activation of β3-adrenoceptor (ADRB3) is essential in the process of human
adipose tissue browning, but obese subjects suffered from reduced ability of brown adipose …

This research was designed to analyze the possible associations of Arg389Gly ADRB1 and
Trp64Arg ADRB3 polymorphisms in children with obesity. A cross-sectional study included …

Highlights•Single nucleotide polymorphisms (SNP) can influence individual responses to
diet.•Gene variants can be used for personalization and optimization of obesity treatment.•A …

Genetic, epigenetic and environmental factors play an important role in the genesis of Type
2 Diabetes Mellitus (T2D). In the genetic context, one of the strategies used to investigate …

Abstract Introduction: the Trp64Arg variant in Beta receptor has been reported to be
associated with increased body weight and insulin resistance Objective: the aim of our study …

Epidemiological studies have suggested that the condition of recurrent pregnancy loss
(RPL) may be multifactorial, with both genetic predisposition and environmental factors …