Polymorphic variants of adrenoceptors: pharmacology, physiology, and role in disease
A Ahles, S Engelhardt - Pharmacological reviews, 2014 - ASPET
The human genome encodes nine different adrenoceptor genes. These are grouped into
three families, namely, the α 1-, α 2-, and β-adrenoceptors, with three family members each …
three families, namely, the α 1-, α 2-, and β-adrenoceptors, with three family members each …
Physiology and pathophysiology of the β3-adrenergic receptor
The β 3-adrenergic receptor (β 3-AR) is an important regulator of various physiological
functions, such as thermogenesis in brown adipose tissue, lipolysis in white adipose tissue …
functions, such as thermogenesis in brown adipose tissue, lipolysis in white adipose tissue …
[HTML][HTML] Future perspectives of personalized weight loss interventions based on nutrigenetic, epigenetic, and metagenomic data
As obesity has become a major global public health challenge, a large number of studies
have analyzed different strategies aimed at inducing a negative energy balance and …
have analyzed different strategies aimed at inducing a negative energy balance and …
[HTML][HTML] ADRB3 polymorphism rs4994 (Trp64Arg) associates significantly with bodyweight elevation and dyslipidaemias in Saudis but not rs1801253 (Arg389Gly) …
M Daghestani, M Daghestani, M Daghistani… - Lipids in health and …, 2018 - Springer
Background In some populations, obesity and body weight related disorders show a
correlation with polymorphisms in three subtypes of beta-adrenoceptor (β1, β2, and …
correlation with polymorphisms in three subtypes of beta-adrenoceptor (β1, β2, and …
[HTML][HTML] Adipocyte ADRB3 down-regulated in chinese overweight individuals adipocyte ADRB3 in overweight
WY Cao, Z Liu, F Guo, J Yu, H Li, X Yin - Obesity facts, 2018 - karger.com
Objectives: Activation of β3-adrenoceptor (ADRB3) is essential in the process of human
adipose tissue browning, but obese subjects suffered from reduced ability of brown adipose …
adipose tissue browning, but obese subjects suffered from reduced ability of brown adipose …
[HTML][HTML] Obesity is associated with the Arg389Gly ADRB1 but not with the Trp64Arg ADRB3 polymorphism in children from San Luis Potosí and León, México
C Aradillas-García, M Cruz, E Pérez-Luque… - Journal of biomedical …, 2017 - ncbi.nlm.nih.gov
This research was designed to analyze the possible associations of Arg389Gly ADRB1 and
Trp64Arg ADRB3 polymorphisms in children with obesity. A cross-sectional study included …
Trp64Arg ADRB3 polymorphisms in children with obesity. A cross-sectional study included …
Genetics of weight loss: A basis for personalized obesity management
JA Martínez, FI Milagro - Trends in Food Science & Technology, 2015 - Elsevier
Highlights•Single nucleotide polymorphisms (SNP) can influence individual responses to
diet.•Gene variants can be used for personalization and optimization of obesity treatment.•A …
diet.•Gene variants can be used for personalization and optimization of obesity treatment.•A …
[HTML][HTML] Investigation of genetic markers associated to type 2 diabetes mellitus in Santarém-Pará
AES Souza, CHS Silva, RCS Oliveira… - … and Molecular Biology, 2024 - SciELO Brasil
Genetic, epigenetic and environmental factors play an important role in the genesis of Type
2 Diabetes Mellitus (T2D). In the genetic context, one of the strategies used to investigate …
2 Diabetes Mellitus (T2D). In the genetic context, one of the strategies used to investigate …
[PDF][PDF] Genetic variation in the beta-3-adrenoreceptor gene (Trp64arg polymorphism) and their influence on anthropometric parameters and insulin resistance after a …
DA de Luis, R Aller, O Izaola, B de la Fuente… - Nutrición …, 2015 - redalyc.org
Abstract Introduction: the Trp64Arg variant in Beta receptor has been reported to be
associated with increased body weight and insulin resistance Objective: the aim of our study …
associated with increased body weight and insulin resistance Objective: the aim of our study …
Maternal folate, alcohol and energy metabolism-related gene polymorphisms and the risk of recurrent pregnancy loss
F Sata, H Yamada, R Kishi… - Journal of developmental …, 2012 - cambridge.org
Epidemiological studies have suggested that the condition of recurrent pregnancy loss
(RPL) may be multifactorial, with both genetic predisposition and environmental factors …
(RPL) may be multifactorial, with both genetic predisposition and environmental factors …