[HTML][HTML] The effect of the tumor microenvironment and tumor-derived metabolites on dendritic cell function

JH Lee, SY Choi, NC Jung, JY Song, HG Seo… - Journal of …, 2020 - ncbi.nlm.nih.gov
Dendritic cells (DCs) have a critical effect on the outcome of adaptive immune responses
against growing tumors. Recent studies on the metabolism on DCs provide new insights on …

Islet culture/preservation before islet transplantation

H Noguchi, C Miyagi-Shiohira, K Kurima… - Cell …, 2015 - journals.sagepub.com
Although islet culture prior to transplantation provides flexibility for the evaluation of isolated
islets and the pretreatment of patients, it is well known that isolated islets deteriorate rapidly …

Beta-cell hubs maintain Ca2+ oscillations in human and mouse islet simulations

CL Lei, JA Kellard, M Hara, JD Johnson, B Rodriguez… - Islets, 2018 - Taylor & Francis
Islet β-cells are responsible for secreting all circulating insulin in response to rising plasma
glucose concentrations. These cells are a phenotypically diverse population that express …

Genetically modified cells, tissues, and organs for treating disease

BJ Hering, C Burlak - US Patent 10,278,372, 2019 - Google Patents
2018-06-19 Assigned to REGENTS OF THE UNIVERSITY OF MINNESOTA reassignment
REGENTS OF THE UNIVERSITY OF MINNESOTA ASSIGNMENT OF ASSIGNORS …

Removal of transmissible spongiform encephalopathy prion from large volumes of cell culture media supplemented with fetal bovine serum by using hollow fiber anion …

ML Chou, A Bailey, T Avory, J Tanimoto, T Burnouf - PLoS One, 2015 - journals.plos.org
Cases of variant Creutzfeldt-Jakob disease in people who had consumed contaminated
meat products from cattle with bovine spongiform encephalopathy emphasize the need for …

Use of additives, scaffolds and extracellular matrix components for improvement of human pancreatic islet outcomes in vitro: A systematic review

NE Lemos, LA Brondani, C Dieter, J Rheinheimer… - Islets, 2017 - Taylor & Francis
Pancreatic islet transplantation is an established treatment to restore insulin independence
in type 1 diabetic patients. Its success rates have increased lately based on improvements in …

Medium supplementation can influence the human ovarian cells in vitro

A Dadashzadeh, S Moghassemi… - Journal of ovarian …, 2022 - Springer
Background Cells are an essential part of the triple principles of tissue engineering and a
crucial component of the engineered ovary as they can induce angiogenesis, synthesize …

Adhesion characteristics of human pancreatic islets, duct epithelial cells, and acinar cells to a polymer scaffold

Y Nakashima, H Iguchi, K Takakura… - Cell …, 2022 - journals.sagepub.com
We reported in 2018 that among several extracellular matrices, fibronectin, type I collagen,
type IV collagen, laminin I, fibrinogen, and bovine serum albumin, fibronectin is particularly …

High seeding density induces local hypoxia and triggers a proinflammatory response in isolated human islets

D Brandhorst, H Brandhorst, N Mullooly… - Cell …, 2016 - journals.sagepub.com
Hypoxia is the main threat to morphological and functional integrity of isolated pancreatic
islets. Lack of oxygen seems to be of particular importance for functionality of encapsulated …

Genetically modified cells, tissues, and organs for treating disease

BJ Hering, C Burlak - US Patent 9,888,673, 2018 - Google Patents
2016-01-28 Assigned to REGENTS OF THE UNIVERSITY OF MINNESOTA reassignment
REGENTS OF THE UNIVERSITY OF MINNESOTA ASSIGNMENT OF ASSIGNORS …