[HTML][HTML] Fundamentals of OA. An initiative of Osteoarthritis and Cartilage. Obesity and metabolic factors in OA

A Batushansky, S Zhu, RK Komaravolu, S South… - Osteoarthritis and …, 2022 - Elsevier
Objective Obesity was once considered a risk factor for knee osteoarthritis (OA) primarily for
biomechanical reasons. Here we provide an additional perspective by discussing how …

[HTML][HTML] Biomechanical considerations in the pathogenesis of osteoarthritis of the knee

A Heijink, AH Gomoll, H Madry, M Drobnič… - Knee Surgery, Sports …, 2012 - Springer
Osteoarthritis is the most common joint disease and a major cause of disability. The knee is
the large joint most affected. While chronological age is the single most important risk factor …

Obesity and knee osteoarthritis

R Lee, WF Kean - Inflammopharmacology, 2012 - Springer
Background The association between obesity and knee osteoarthritis, and specifically the
role of obesity as a risk factor for knee osteoarthritis has been well documented. A …

[HTML][HTML] Osteoarthritis: novel molecular mechanisms increase our understanding of the disease pathology

S Grässel, F Zaucke, H Madry - Journal of clinical medicine, 2021 - mdpi.com
Although osteoarthritis (OA) is the most common musculoskeletal condition that causes
significant health and social problems worldwide, its exact etiology is still unclear. With an …

Relationship between knee biomechanics and pain in people with knee osteoarthritis: a systematic review and meta‐analysis

L Hutchison, J Grayson, C Hiller… - Arthritis care & …, 2023 - Wiley Online Library
Objective Our primary aim was to determine the cross‐sectional relationship between knee
biomechanics during gait and pain in people with medial knee osteoarthritis. Our secondary …

Patellofemoral osteoarthritis is prevalent and associated with worse symptoms and function after hamstring tendon autograft ACL reconstruction

AG Culvenor, CCH Lai, BJ Gabbe… - British journal of sports …, 2014 - bjsm.bmj.com
Objectives To evaluate the compartmental distribution of knee osteoarthritis (OA) after
anterior cruciate ligament reconstruction (ACLR), to determine if patellofemoral or …

High tibial osteotomy: evolution of research and clinical applications—a Canadian experience

I McNamara, TB Birmingham, PJ Fowler… - Knee Surgery, Sports …, 2013 - Springer
Purpose This narrative review describes experiences at the Fowler Kennedy Sport Medicine
Clinic (FKSMC) with high tibial osteotomy (HTO) for patients with varus gonarthrosis, with …

[PDF][PDF] Modulation of the relationship between external knee adduction moments and medial joint contact forces across subjects and activities

A Trepczynski, I Kutzner, G Bergmann… - Arthritis & …, 2014 - Wiley Online Library
Objective The external knee adduction moment (EAM) is often considered a surrogate
measure of the distribution of loads across the tibiofemoral joint during walking. This study …

[HTML][HTML] The factors associated with pain severity in patients with knee osteoarthritis vary according to the radiographic disease severity: a cross-sectional study

Y Shimura, H Kurosawa, Y Sugawara… - Osteoarthritis and …, 2013 - Elsevier
Objectives Knee osteoarthritis (OA) pain is suggested to be associated with inflammation
and detrimental mechanical loading across the joint. In this cross-sectional study, we …

Using cumulative load to explain how body mass index and daily walking relate to worsening knee cartilage damage over two years: the MOST study

D Voinier, T Neogi, JJ Stefanik… - Arthritis & …, 2020 - Wiley Online Library
Objective Knee cartilage damage is often linked to mechanical overloading. However,
cartilage requires mechanical load to remain healthy, suggesting that underloading may be …