[HTML][HTML] Bridging bench to body: ex vivo models to understand articular cartilage repair
Highlights•Novel articular cartilage tissue engineering therapies have been
developed.•Integration of engineered tissue with native cartilage is an ongoing …
developed.•Integration of engineered tissue with native cartilage is an ongoing …
[HTML][HTML] Advanced therapy with mesenchymal stromal cells for knee osteoarthritis: Systematic review and meta-analysis of randomized controlled trials
CG Tabet, RL Pacheco, ALC Martimbianco… - Journal of Orthopaedic …, 2024 - Elsevier
Background Advanced cell therapies emerged as promising candidates for treatment of
knee articular diseases, but robust evidence regarding their clinical applicability is still …
knee articular diseases, but robust evidence regarding their clinical applicability is still …
Pulsed electromagnetic fields potentiate bone marrow mesenchymal stem cell chondrogenesis by regulating the Wnt/β-catenin signaling pathway
K Song, J Hu, M Yang, Y Xia, C He, Y Yang… - Journal of Translational …, 2024 - Springer
Abstract Background Pulsed electromagnetic fields (PEMFs) show promise as a treatment
for knee osteoarthritis (KOA) by reducing inflammation and promoting chondrogenic …
for knee osteoarthritis (KOA) by reducing inflammation and promoting chondrogenic …
Curcumin-loaded porous scaffold: an anti-angiogenic approach to inhibit endochondral ossification
J Zhou - Journal of Biomaterials Science, Polymer Edition, 2023 - Taylor & Francis
Bone marrow stem cells (BMSCs) are recognized for their robust proliferative capabilities
and multidirectional differentiation potential. Ectopic endochondral ossification of BMSC …
and multidirectional differentiation potential. Ectopic endochondral ossification of BMSC …
Increased physiological osteochondral repair via space-specific sequestrating endogenous BMP-2 founctional hydrogel
Y Wang, Y Lei, N Wang, J Zhang, W Cui… - Chemical Engineering …, 2024 - Elsevier
The challenge of achieving graded regeneration of adjacent tissues remains significant in
tissue repair and regeneration. For instance, the disruption of the microenvironment caused …
tissue repair and regeneration. For instance, the disruption of the microenvironment caused …
Exosomes Derived from Bone Marrow Mesenchymal Stem Cells Alleviate Rheumatoid Arthritis Symptoms via Shuttling Proteins
L Wang, F Li, L Wang, B Wu, M Du… - Journal of Proteome …, 2024 - ACS Publications
Our prior investigations have evidenced that bone marrow mesenchymal stem cell (BMSC)
therapy can significantly improve the outcomes of rheumatoid arthritis (RA). This study aims …
therapy can significantly improve the outcomes of rheumatoid arthritis (RA). This study aims …
Exploring Orthopedic Stem-Cell Approaches for Osteoarthritis Management: Current Trends and Future Horizons
M Ehioghae, TK Vippa, D Askins, S Slusarczyk… - Current Pain and …, 2024 - Springer
Abstract Purpose of Review Osteoarthritis (OA) is a prevalent and debilitating condition
characterized by joint degeneration and pain. Current treatment options aim to alleviate …
characterized by joint degeneration and pain. Current treatment options aim to alleviate …
Temporal control in shell–core structured nanofilm for tracheal cartilage regeneration: synergistic optimization of anti-inflammation and chondrogenesis
W Zhao, F Xu, Y Shen, Q Ding, Y Wang… - Regenerative …, 2024 - academic.oup.com
Cartilage tissue engineering offers hope for tracheal cartilage defect repair. Establishing an
anti-inflammatory microenvironment stands as a prerequisite for successful tracheal …
anti-inflammatory microenvironment stands as a prerequisite for successful tracheal …
The Efficacy of Bone Marrow Stem Cell Therapy in Hip Osteoarthritis: A Scoping Review
OF Perez, C Warburton, MC Philippon Jr… - HSS Journal …, 2024 - journals.sagepub.com
Background: Hip osteoarthritis (HOA) is a prevalent degenerative joint disease with various
treatment approaches. Biological agents, such as bone-marrow derived stem cells (BM …
treatment approaches. Biological agents, such as bone-marrow derived stem cells (BM …
Mesenchymal Stromal Cell Immunomodulatory Potential for Orthopedic Applications can be fine-tuned via 3D nano-engineered Scaffolds
F Banche-Niclot, J Lim, P McCulloch… - Current Stem Cell …, 2024 - Springer
Nanostructured 3D scaffolds characterized by nano topography, roughness, high porosity,
biomimetic stiffness and chemistry, offer a sophisticated means to optimize the …
biomimetic stiffness and chemistry, offer a sophisticated means to optimize the …