The fibroblast growth factor signaling pathway

DM Ornitz, N Itoh - Wiley Interdisciplinary Reviews …, 2015 - Wiley Online Library
The signaling component of the mammalian Fibroblast Growth Factor (FGF) family is
comprised of eighteen secreted proteins that interact with four signaling tyrosine kinase FGF …

The impact of transposable elements in adaptive evolution

L Schrader, J Schmitz - Molecular Ecology, 2019 - Wiley Online Library
The growing knowledge about the influence of transposable elements (TE s) on (a) long‐
term genome and transcriptome evolution;(b) genomic, transcriptomic and epigenetic …

Ancestry-inclusive dog genomics challenges popular breed stereotypes

K Morrill, J Hekman, X Li, J McClure, B Logan… - Science, 2022 - science.org
Behavioral genetics in dogs has focused on modern breeds, which are isolated subgroups
with distinctive physical and, purportedly, behavioral characteristics. We interrogated breed …

Genomic and archaeological evidence suggest a dual origin of domestic dogs

LAF Frantz, VE Mullin, M Pionnier-Capitan… - Science, 2016 - science.org
The geographic and temporal origins of dogs remain controversial. We generated genetic
sequences from 59 ancient dogs and a complete (28x) genome of a late Neolithic dog …

[HTML][HTML] Genomic analyses reveal the influence of geographic origin, migration, and hybridization on modern dog breed development

HG Parker, DL Dreger, M Rimbault, BW Davis… - Cell reports, 2017 - cell.com
There are nearly 400 modern domestic dog breeds with a unique histories and genetic
profiles. To track the genetic signatures of breed development, we have assembled the most …

Genome sequencing of 2000 canids by the Dog10K consortium advances the understanding of demography, genome function and architecture

JRS Meadows, JM Kidd, GD Wang, HG Parker… - Genome biology, 2023 - Springer
Abstract Background The international Dog10K project aims to sequence and analyze
several thousand canine genomes. Incorporating 20× data from 1987 individuals, including …

Rethinking dog domestication by integrating genetics, archeology, and biogeography

G Larson, EK Karlsson, A Perri… - Proceedings of the …, 2012 - National Acad Sciences
The dog was the first domesticated animal but it remains uncertain when the domestication
process began and whether it occurred just once or multiple times across the Northern …

Molecular genetic variation of animals and plants under domestication

L Andersson, M Purugganan - Proceedings of the National …, 2022 - National Acad Sciences
Domesticated plants and animals played crucial roles as models for evolutionary change by
means of natural selection and for establishing the rules of inheritance, originally proposed …

Active human retrotransposons: variation and disease

DC Hancks, HH Kazazian Jr - Current opinion in genetics & development, 2012 - Elsevier
Mobile DNAs, also known as transposons or 'jumping genes', are widespread in nature and
comprise an estimated 45% of the human genome. Transposons are divided into two …

Origins, evolution, and phenotypic impact of new genes

H Kaessmann - Genome research, 2010 - genome.cshlp.org
Ever since the pre-molecular era, the birth of new genes with novel functions has been
considered to be a major contributor to adaptive evolutionary innovation. Here, I review the …