The global prevalence of atrial fibrillation (AF) has increased substantially over the past
three decades and is currently approximately 60 million cases. Incident AF and its clinical …

The sequencing of the human genome has allowed the study of the genetic architecture of
common diseases: the number of genomic variants that contribute to risk of disease and …

Abstract Aim The “2023 ACC/AHA/ACCP/HRS Guideline for the Diagnosis and Management
of Patients With Atrial Fibrillation” provides recommendations to guide clinicians in the …

Elevated blood pressure and hypertension have been associated with increased risk of
atrial fibrillation in a number of epidemiological studies, however, the strength of the …

A true discrepancy between the effect of systolic blood pressure (SBP) and diastolic blood
pressure (DBP) on cardiovascular (CV) outcomes remains unclear. This study performed …

Arterial stiffness has been investigated as part of the physiopathology of arterial
hypertension since the 1970s. Its role in increasing the “pulsatile load” imposed over the Left …

Background Observational associations between type 2 diabetes (T2D) and atrial fibrillation
(AF) have been established, but causality remains undetermined. We performed Mendelian …

Background Kidney stone disease (KSD) has been reported to be associated with several
cardiovascular diseases. However, the causality between the conditions remains unknown …

Introduction: Hypertension (HT) and atrial fibrillation (AF) often coexist. However, the
causality between these two conditions remains to be determined. Methods: We used …

* Writing committee members are required to recuse themselves from voting on sections to
which their specific relationships with industry may apply; see Appendix 1 for detailed …